Evidence map›Paper›PMID 32005667›Full record

ArticleThe Journal of biological chemistry2020

Functional analysis of

Chia-Yu Kang, I-Hsiu Huang, Chi-Chi Chou, Tsai-Yu Wu, Jyun-Cyuan Chang, Yu-Yuan Hsiao, Cheng-Hsuan Cheng, Wei-Jiun Tsai, Kai-Cheng Hsu, Shuying Wang

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Functional Characterization of a Putative Sortase FA1364 inInternational journal of molecular sciences · 2026
    Article
  2. Journal of oral microbiology · 2025
    Article
  3. Rising prevalence and drug resistance ofFrontiers in cellular and infection microbiology · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Chia-Yu KangDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan 701, Taiwan.
I-Hsiu HuangDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan 701, Taiwan.
Chi-Chi ChouInstitute of Biological Chemistry, Academia Sinica, Nankang, Taipei 115, Taiwan.
Tsai-Yu WuDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan 701, Taiwan.
Jyun-Cyuan ChangDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan 701, Taiwan.
Yu-Yuan HsiaoInstitute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan; Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 300, Taiwan; Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, Hsinchu 300, Taiwan.
Cheng-Hsuan ChengDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan 701, Taiwan; Institute of Basic Medical Science, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.
Wei-Jiun TsaiDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan 701, Taiwan; Institute of Basic Medical Science, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.
Kai-Cheng HsuGraduate Institute of Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
Shuying WangDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan 701, Taiwan; Institute of Basic Medical Science, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. Electronic address: sswang23@mail.ncku.edu.tw.
National Cheng Kung University · TWInstitute of Biological Chemistry, Academia Sinica · TWNational Yang Ming Chiao Tung University · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most of Gram-positive bacteria anchor surface proteins to the peptidoglycan cell wall by sortase, a cysteine transpeptidase that targets proteins displaying a cell wall sorting signal. Unlike other bacteria,

Indexed as

BiocatalysisAmino AcidsAmino Acid SequenceAminoacyltransferasesBacterial ProteinsClostridioides difficileConserved SequenceCrystallography, X-RayCysteine EndopeptidasesMutationProtein Structure, SecondarySerineStructure-Activity RelationshipSubstrate SpecificityAmino AcidsAminoacyltransferasesBacterial ProteinsCysteine EndopeptidasesSerinesortase BClostridium difficilecrystal structurecysteine transpeptidaseenzyme catalysisfluorescence resonance energy transfer (FRET)protein chemistryprotein purificationprotein sortingprotein structuresortase Bsubstrate specificity

Identifiers

PMID32005667
PMCPMC7076211
OpenAlexW3004099047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.