ReviewThe Journal of biological chemistry2020
How and why to build a mathematical model: A case study using prion aggregation.
Review in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of the Efforts and Hindrances of Modeling and Simulation of CAR T-cell Therapy.The AAPS journal · 2021Pooled it
- The Hill-Type Equation Reveals the Regulatory Principle of Target Protein Expression Led by p53 Pulsing.FASEB bioAdvances · 2025Article
- Supercritical Carbon Dioxide Extraction of Coumarins from the Aerial Parts ofMolecules (Basel, Switzerland) · 2024Article
- MIL-CELL: a tool for multi-scale simulation of yeast replication and prion transmission.European biophysics journal : EBJ · 2023Article
- Different Trajectories for Diabetes Mellitus Onset and Recovery According to the Centralized Aerobic-Anaerobic Energy Balance Compensation Theory.Biomedicines · 2023Article
- Understanding fibrosis pathogenesis via modeling macrophage-fibroblast interplay in immune-metabolic context.Nature communications · 2022Article
- A group theoretic approach to model comparison with simplicial representations.Journal of mathematical biology · 2022Article
- Analysis of steady-state carbon tracer experiments using akaike information criteria.Metabolomics : Official journal of the Metabolomic Society · 2021Article
- The Art and Science of Building a Computational Model to Understand Hemostasis.Seminars in thrombosis and hemostasis · 2021Review
- Lost in modelling and simulation?ADMET & DMPK · 2021Article
- Mathematical Modeling of a Supramolecular Assembly for Pyrophosphate Sensing.Frontiers in chemistry · 2021Article
- Towards Generative Design of Computationally Efficient Mathematical Models with Evolutionary Learning.Entropy (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Biological systems are inherently complex, and the increasing level of detail with which we are able to experimentally probe such systems continually reveals new complexity. Fortunately, mathematical models are uniquely positioned to provide a tool suitable for rigorous analysis, hypothesis generation, and connecting results from isolated
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.