Evidence map›Paper›PMID 32005537›Full record

ArticleVaccine2020

Isolation and characterization of new human carrier peptides from two important vaccine immunogens.

Paeton L Wantuch, Lina Sun, Rachel K LoPilato, Jarrod J Mousa, Robert S Haltiwanger, Fikri Y Avci

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Paeton L WantuchDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA; Center for Molecular Medicine, University of Georgia, Athens, GA 30602, USA.
Lina SunDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA; Center for Molecular Medicine, University of Georgia, Athens, GA 30602, USA.
Rachel K LoPilatoDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA; Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602, USA.
Jarrod J MousaCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Robert S HaltiwangerDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA; Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602, USA.
Fikri Y AvciDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA; Center for Molecular Medicine, University of Georgia, Athens, GA 30602, USA. Electronic address: avci@uga.edu.
University of Georgia · US

Funding

O-Glycosylation of Epidermal Growth Factor-like MotifsR01GM061126 · NIGMS · UNIVERSITY OF GEORGIA · PI HALTIWANGER, ROBERT S. · 2001 to 2021
$9.1M
Molecular Mechanisms for Carbohydrate Presentation to CD4+ T cells by MHCII PathwayR01AI123383 · NIAID · UNIVERSITY OF GEORGIA · PI Fikri Y Avci · 2016 to 2026
$4.2M
Glycopeptide-specific helper T cells eliciting protective humoral immunity against HIV - ResubmissionR01AI152766 · NIAID · UNIVERSITY OF GEORGIA · PI Fikri Y Avci · 2021 to 2026
$2.6M
Glycoscience Training ProgramT32GM107004 · NIGMS · UNIVERSITY OF GEORGIA · PI AMSTER, I JONATHAN, HALTIWANGER, ROBERT S. · 2014 to 2021
$1.3M
Therapeutic antibodies to treat Pneumocystis pneumonia in a nonhuman primate model of HIV infectionK01OD026569 · OD · UNIVERSITY OF GEORGIA · PI MOUSA, JARROD · 2018 to 2020
$1.0M
NIAID NIH HHS R01 AI123383NIAID NIH HHS R01 AI152766NIGMS NIH HHS R01 GM061126NIGMS NIH HHS T32 GM107004NIH HHS K01 OD026569
6 · The paper itself

Abstract

In the preparation of glycoconjugate vaccines in clinical practice, two highly immunogenic carrier proteins, CRM

Indexed as

Epitopes, T-LymphocyteAdultAntigen PresentationBacterial ProteinsCD4-Positive T-LymphocytesGlycoconjugatesHistocompatibility Antigens Class IIHumansMalePeptide LibraryPeptidesTetanus ToxoidBacterial ProteinsCRM197 (non-toxic variant of diphtheria toxin)Epitopes, T-LymphocyteGlycoconjugatesHistocompatibility Antigens Class IIPeptide LibraryPeptidesTetanus ToxoidB cellCarrier proteinCRM(197)Glycoconjugate vaccinesMHC class IIT cellTetanus toxoid

Identifiers

PMID32005537
PMCPMC7059840
OpenAlexW3003558555

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.