ArticleInfectious diseases of poverty2020
Incidence and risk factors of tuberculosis among the elderly population in China: a prospective cohort study.
Article in Infectious diseases of poverty, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.
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Who cites it
48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Body mass index and tuberculosis risk: an updated systematic literature review and dose-response meta-analysis.International journal of epidemiology · 2025Pooled it
- Undernutrition as a risk factor for tuberculosis disease.The Cochrane database of systematic reviews · 2024Pooled it
- Tuberculosis in Sudan: systematic review and meta analysis.BMC pulmonary medicine · 2024Pooled it
- Active Case Finding for Tuberculosis in Migrants: a Systematic Review.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2024Pooled it
- Tuberculosis preventive treatment among individuals with inactive tuberculosis suggested by untreated radiographic abnormalities: a community-based randomized controlled trial.Emerging microbes & infections · 2023Trial
- Comorbidity profiles and their impact on treatment outcomes in elderly patients with pulmonary tuberculosis: a single-center retrospective cohort study.BMC infectious diseases · 2026Article
- Dupilumab in Elderly Patients with Atopic Dermatitis-A Systematic Review and Meta-Analysis.Biomedicines · 2026Review
- Pre-screening village tuberculosis notification rates and the yield of interferon-gamma release assay testing in a rural health-examination campaign in Xinjiang, China.Frontiers in public health · 2026Article
- Frailty and its multidimensional correlates among hospitalized older adults with pulmonary tuberculosis: a cross-sectional study.Frontiers in medicine · 2026Article
- Tuberculosis disease burden trends, drivers, and projections to 2050 in China and the wider Central Asian region, 1990-2023.PloS one · 2026Article
- Prediction of Tuberculosis Risk in the Elderly Population of Eastern China: Development and Validation of Multiple Machine Learning Models.Infection and drug resistance · 2026Article
- Article
- Trend analysis of changes in the incidence of tuberculosis in Shenzhen from 2010 to 2020 based on the Joinpoint regression model.BMC public health · 2025Article
- Analysis of factors influencing high infectivity in patients with tuberculosis using clinical and imaging methods.BMC infectious diseases · 2025Article
- Analyzing factors affecting tuberculosis incidence in various mainland Chinese economic regions and predicting trends: a comprehensive regression study.BMC public health · 2025Article
- Risk of tuberculosis in individuals with type 2 diabetes mellitus based on the tuberculosis predictive index score: a case-control study in Indonesia.Osong public health and research perspectives · 2025Article
- Trends and delays in pulmonary tuberculosis diagnosis among elderly patients (≥ 60 Years) in Southern China: a 13-year surveillance data analysis (2010-2022).BMC public health · 2025Article
- Clinical characteristics and risk factors analysis of bilateral renal tuberculosis.International urology and nephrology · 2025Article
- Social participation and exposure to tuberculosis education: a cross-sectional study of older (≥ 60 years) domestic migrants in China.BMC public health · 2025Article
- Observational
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17 authors at 11 institutions in 1 country.
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Abstract
backgroundChina is facing challenges of the shifting presentation of tuberculosis (TB) from younger to elderly due to an ageing population, longer life expectancy and reactivation disease. However, the burden of elderly TB and influence factors are not yet clear. To fill the gap, we generated a cohort study to measure the magnitude of TB incidence and associated factors among the elderly population aged 65 years and above in China.
methodsIn this cohort established in 2013 through a prevalence survey conducted in selected sites, a total of 34 076 elderlies without TB were enrolled into two-year follow-up. We used both active and passive case findings to find out all TB patients among them. The person-year (PY) incidence rates for both bacteriologically positive TB and active TB were calculated. Cox proportional regression model was performed to test effect of risk factors, and the population attributable fraction (PAF) of each risk factor contributing to incident TB among elderlies was calculated.
resultsOver the two-year follow-up period, a total of 215 incident active TB were identified, 62 of which were bacteriologically positive. The incidence rates for active TB and bacteriologically positive TB were 481.8 per 100 000 PY (95% CI: 417.4-546.2 per 100 000 PY) and 138.9 per 100 000 PY (95% CI: 104.4-173.5 per 100 000 PY), respectively. Incident cases detected by active case finding were significantly higher (P < 0.001). Male, non-Han nationality, previously treated TB, ex/current smoker and body mass index (BMI) < 18.5 presented as independent predictors for developing TB disease. For developing bacteriologically positive TB, the biggest contribution was from self-reported ex or current smoker (18.06%). And, for developing active TB, the biggest contribution was from non-Han nationality (35.40%), followed by male (26.80%) and age at 75 years and above (10.85%).
conclusionsAgeing population in China had a high TB incidence rate and risk to develop TB disease, implying that National TB Program (NTP) needs to prioritize for elderly. Active case finding should be applied capture more active TB cases among this particular population, especially for male, non-Han nationality, and those with identified risk factors.
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