ArticleJournal of orthopaedic surgery and research2020
The clinical outcomes of cementless unicompartmental knee replacement in patients with reduced bone mineral density.
Article in Journal of orthopaedic surgery and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04694625 (Effects of Structured Rehabilitation Program on Pain and Function in Patients With Total Knee Replacement), which is not on this map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Structured Rehabilitation Program on Pain and Function in Patients With Total Knee Replacement
Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Trial
- Tibial implant migration of cemented and cementless total and unicompartmental knee arthroplasties in patients with low and normal bone mineral density: a 5-year RSA cohort study of 397 cases.Acta orthopaedica · 2026Article
- Long-term outcomes of a 3D printed cementless fixed bearing unicompartmental knee arthroplasty.Archives of orthopaedic and trauma surgery · 2025Article
- Influencing factors on the quality of recovery after total knee arthroplasty: development of a predictive model.Frontiers in medicine · 2024Article
- The Effect of Resistance Training on Bone Mineral Density in Older Adults: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2022Review
- The effect of age on the outcomes of cementless mobile bearing unicompartmental knee replacements.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
- Does gender influence the outcomes of total ankle arthroplasty in patients with ankle osteoarthritis?Journal of orthopaedic surgery and research · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoporosis and osteopenia are conditions characterised by reduced bone mineral density (BMD). There is concern that bone with reduced BMD may not provide sufficient fixation for cementless components which primarily rely on the quality of surrounding bone. The aim of our study was to report the midterm clinical outcomes of patients with reduced BMD undergoing cementless unicompartmental knee replacements (UKR). Our hypothesis was that there would be no difference in outcome between patients with normal bone and those with reduced BMD.
methodsFrom a prospective cohort of 70 patients undergoing cementless UKR surgery, patients were categorised into normal (n = 20), osteopenic (n = 38) and osteoporotic groups (n = 12) based on their central dual-energy X-ray absorptiometry (DEXA) scans according to the World Health Organization criteria. Patients were followed up by independent research physiotherapists and outcome scores; Oxford Knee Score (OKS), Tegner score, American Knee Society Score Functional (AKSS-F) and Objective (AKSS-O) were recorded preoperatively and at a mean of 4 years postoperatively. The prevalence of reoperations, revisions and mortality was also recorded at a mean of 5 years postoperatively.
resultsThere were no significant differences in the midterm postoperative OKS (P = 0.83), Tegner score (P = 0.17) and AKSS-O (P = 0.67). However, the AKSS-F was significantly higher (P = 0.04) in normal (90, IQR 37.5) compared to osteoporotic (65, IQR 35) groups. There were no significant differences (P = 0.82) between normal and osteopenic bone (80, IQR 35). The revision prevalence was 5%, 2.6% and 0% in the normal, osteopenic and osteoporotic groups respectively. The reoperation prevalence was 5%, 7.9% and 0% respectively. There were no deaths in any group related to the implant.
conclusionsWe found that patients with reduced BMD could safely undergo cementless UKR surgery and have similar clinical outcomes to those with normal BMD. However, larger studies with longer follow-up are needed to confirm our findings and ensure that cementless fixation is safe in patients with reduced BMD.
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