ArticlePloS one2020
Aspects of diastolic dysfunction in patients with new and recurrent depression.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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16 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
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- Relationship Between Depression and Decreased Activity Level and Cognitive Impairment in Patients with Diabetes Mellitus Type 2 and/or Atrial Fibrillation.Journal of clinical medicine · 2025Article
- Cognitive Function Profiles and Associated Factors in Older Adults Living with Type 2 Diabetes: A Latent Profile Analysis.Clinical interventions in aging · 2025Article
- Factors Influencing the Development and Severity of Cognitive Decline in Patients with Chronic Heart Failure.Medicina (Kaunas, Lithuania) · 2024Article
- Analysis of Related Factors Influencing Hypertension Classification among Centenarians in Hainan, China.Reviews in cardiovascular medicine · 2024Article
- The Contribution of Genetic Testing in Optimizing Therapy for Patients with Recurrent Depressive Disorder.Clinics and practice · 2024Article
- Connections between Cognitive Impairment and Atrial Fibrillation in Patients with Diabetes Mellitus Type 2.Biomedicines · 2024Article
- Neurocognitive impairment and its associated factors among patients with diabetes mellitus who have follow up at referral hospital in Northwest, Ethiopia.Frontiers in endocrinology · 2024Article
- Evaluation of Arterial Stiffness in Depression Patients.Alpha psychiatry · 2023Article
- Increased 10-year cardiovascular disease risk in depressed patients with coexisting subclinical hypothyroidism.Frontiers in psychiatry · 2023Article
- The practical utility of psychometric scales for the assessment of the impact of posttraumatic scars on mental health.Frontiers in public health · 2023Article
- Assessment of the Impact of Alcohol Consumption Patterns on Heart Rate Variability by Machine Learning in Healthy Young Adults.Medicina (Kaunas, Lithuania) · 2021Article
- Social Inferences as Mediators of Wellbeing in Depression.Neuropsychiatric disease and treatment · 2021Article
- Evolution of Heart Rate Variability and Heart Rate Turbulence in Patients with Depressive Illness Treated with Selective Serotonin Reuptake Inhibitors.Medicina (Kaunas, Lithuania) · 2020Article
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4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveThe main objective of this study was to evidence the potential impact of the intensity, duration and recurrence of depression on the development of arterial stiffness (AS) leading to left ventricular hypertrophy (LVH) and diastolic dysfunction (DD) in patients with new onset depression (NOD) and recurrent depression (RD) in comparison to 33 control subjects without depression. Another aim was to identify potential predictive factors regarding the occurrence of diastolic dysfunction (DD).
methodsOur study group included 58 patients diagnosed with NOD and 128 diagnosed with RD, without any previously diagnosed significant heart diseases. The intensity of depression was evaluated by means of the Montgomery-Asberg Depression Rating Scale (MADRS). Assessment of pulse wave velocity (PWV), left ventricular mass index (LVMI) and echocardiographic parameters characterizing DD were performed for each patient.
resultsThe cardiology evaluations suggested an increased prevalence of AS in all patients, of significantly higher rate than in controls (p<0.001), which was statistically correlated with the severity and duration of depression. Another significant finding was an increased prevalence of DD (29.31% and 63.28%, respectively; p<0.001) correlated with the MADRS score, total duration and number of recurrences/relapses. The multivariate logistic regression analysis identified PWV, the intensity and duration of depression as significant predictive factors for the occurrence of DD.
conclusionsIn our study, diastolic dysfunction was a common finding among patients with RD, but it was also noted, to a lesser extent, in those suffering with NOD. DD was associated with altered AS, and strongly correlated with the intensity and the duration of depressive symptoms. The two latter factors, together with an increased PWV, were strong predictors for the occurrence of DD.
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