Evidence map›Paper›PMID 32004963›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2020

Serum concentrations of persistent organic pollutants and the metabolic syndrome in Akwesasne Mohawks, a Native American community.

Zafar Aminov, David O Carpenter

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. A Review of Polychlorinated Biphenyls (PCBs) Pollution in the Air: Where and How Much Are We Exposed to?International journal of environmental research and public health · 2022
    Review
  11. Article
  12. Article
  13. Understanding Historical Trauma Among Urban Indigenous Adults at Risk for Diabetes.American Indian and Alaska native mental health research (Online) · 2022
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zafar AminovDepartment of Environmental Health Sciences, School of Public Health, USA.
David O CarpenterDepartment of Environmental Health Sciences, School of Public Health, USA; Institute for Health and the Environment, University at Albany, 5 University Place, Rensselaer, NY, 12144, USA. Electronic address: dcarpenter@albany.edu.
University at Albany, State University of New York · US

Funding

TRANSPORT AND FATE OF ORGANIC CONTAMINANTS THROUGH SOIL/ROCK SYSTEMSP42ES004913 · NIEHS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI CARPENTER, DAVID ORLO · 1990 to 2001
$331k
NIEHS NIH HHS P42 ES004913
6 · The paper itself

Abstract

The metabolic syndrome (MetS) is a group of diseases that tend to occur together, including diabetes, hypertension, central obesity, cardiovascular disease and hyperlipidemia. Exposure to persistent organic pollutants (POPs) such as polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) has been associated with increased risk of development of several of the components of the MetS. The goal of this study is to determine whether the associations with POPs are identical for each of the components and for the MetS. The subject population was 601 Native Americans (Akwesasne Mohawks) ages 18 to 84 who answered a questionnaire, were measured for height and weight and provided blood samples for clinical chemistries (serum lipids and fasting glucose) and analysis of 101 PCB congeners and three OCPs [dichlorodiphenyldichloroethylene (DDE), hexachlorobenzene (HCB) and mirex]. Associations between concentrations of total PCBs and pesticides, as well as various PCB congener groups with each of the different components of the MetS were determine so as to ask whether there were similar risk factors for all components of the MetS. After adjustment for other contaminants, diabetes and hypertension were strongly associated with lower chlorinated and mono-ortho PCBs, but not other PCB groups or pesticides. Obesity was most closely associated with highly chlorinated PCBs and was negatively associated with mirex. High serum lipids were most strongly associated with higher chlorinated PCBs and PCBs with multiple ortho-substituted chlorines, as well as total pesticides, DDE and HCB. Cardiovascular disease was not closely associated with levels of any of the measured POPs. While exposure to POPs is associated with increased risk of most of the various diseases comprising the MetS, the specific contaminants associated with risk of the component diseases are not the same.

Indexed as

AdolescentAdultAgedAged, 80 and overEnvironmental ExposureEnvironmental PollutantsHumansHydrocarbons, ChlorinatedIndians, North AmericanMetabolic SyndromeMiddle AgedPesticidesPolychlorinated BiphenylsUnited StatesYoung AdultEnvironmental PollutantsHydrocarbons, ChlorinatedPesticidesPolychlorinated BiphenylsDiabetesHyperlipidemiaHypertensionNative AmericansObesity

Identifiers

PMID32004963
PMCPMC10658355
OpenAlexW3001937260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.