Evidence map›Paper›PMID 32004742›Full record

ArticleWorld neurosurgery2020

Effects of Negative Pressure Wound Therapy on Wound Dehiscence and Surgical Site Infection Following Instrumented Spinal Fusion Surgery-A Single Surgeon's Experience.

Ryan M Naylor, Hannah E Gilder, Nikita Gupta, Thomas C Hydrick, Joshua R Labott, David J Mauler, Taylor P Trentadue, Brandon Ghislain, Benjamin D Elder, Jeremy L Fogelson

Open access · greenAbstract read
In one paragraph

Article in World neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Negative pressure wound therapy in the management of postoperative spinal wound infections: a systematic review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Pooled it
  2. Pooled it
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  4. Can prophylactic negative pressure wound therapy improve clinical outcomes in spinal fusion surgery? A meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Pooled it
  5. Review
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  11. Negative Pressure Wound Therapy in Spinal Surgery.Bioengineering (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Negative pressure wound therapy in cases of spinal surgery and exposed dura: a case-based review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ryan M NaylorDepartment of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Hannah E GilderDepartment of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Nikita GuptaMayo Clinic Alix School of Medicine, Mayo Clinic, Scottsdale, Arizona, USA.
Thomas C HydrickMayo Clinic Alix School of Medicine, Mayo Clinic, Scottsdale, Arizona, USA.
Joshua R LabottMayo Clinic Alix School of Medicine, Rochester, Minnesota, USA.
David J MaulerMayo Clinic Alix School of Medicine, Mayo Clinic, Scottsdale, Arizona, USA.
Taylor P TrentadueMayo Clinic Alix School of Medicine, Rochester, Minnesota, USA; Mayo Clinic Medical Scientist Training Program, Rochester, Minnesota, USA.
Brandon GhislainMayo Clinic Alix School of Medicine, Rochester, Minnesota, USA.
Benjamin D ElderDepartment of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Orthopedic Surgery, Rochester, Minnesota, USA; Department of Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA.
Jeremy L FogelsonDepartment of Neurological Surgery, Mayo Clinic, Rochester, Minnesota, USA; Department of Orthopedic Surgery, Rochester, Minnesota, USA. Electronic address: fogelson.jeremy@mayo.edu.
Mayo Clinic · USMayo Clinic in Arizona · US

Funding

Medical Scientist Traning Program at Mayo ClinicT32GM065841 · NIGMS · MAYO CLINIC ROCHESTER · PI KAUFMANN, SCOTT H, SCHIMMENTI, LISA A · 2003 to 2022
$5.8M
NIGMS NIH HHS T32 GM065841
6 · The paper itself

Abstract

backgroundIncisional negative pressure wound therapy (NPWT) is used in many surgical specialties to prevent postoperative dehiscence and surgical site infections (SSIs). However, little is known about the role of incisional NPWT in spine fusion surgery. Therefore, we sought to report a single surgeon's experience using incisional NPWT and describe its effects on dehiscence and SSIs after instrumented spine surgery.

methodsWe compared rates of hospital readmission and return to the operating room for dehiscence and SSIs in a consecutive series of patients who underwent spinal fusion surgery with or without NPWT from 2015 to 2018.

resultsA total of 393 patients without and 76 patients with NPWT were included for analysis. Half way through the data collection period, all patients who underwent anterior lumbar fusion received NPWT. Three of 15 (20.0%) of non-NPWT patients who underwent anterior lumbar fusion had dehiscence or SSI compared with zero of 23 (0.0%) of NPWT patients (P = 0.01). NPWT for posterior surgeries was used on a case-by-case basis using risk factors that contribute to SSIs and dehiscence. NPWT patients had higher rates of spinal neoplasia (0.5% vs. 11.3%, P < 0.0001), osteomyelitis/diskitis (1.3% vs. 7.5%, P = 0.02), durotomy (14.9% vs. 28.6%, P = 0.007), revision surgery (32.2% vs. 59.6%, P = 0.0001), and longer fusion constructs (7 vs. 11 levels, P < 0.0001) but had similar rates of dehiscence and SSIs as non-NPWT patients (5.6% vs. 5.7%, P = 0.98).

conclusionsNPWT decreases dehiscence and SSIs in patients undergoing lumbar fusion through an anterior approach. When preferentially used in patients at high risk for postoperative wound complications, NPWT prevents increased rates of dehiscence and SSI.

Indexed as

AgedCase-Control StudiesCohort StudiesDiscitisDura MaterFemaleHumansLumbar VertebraeMaleMiddle AgedNegative-Pressure Wound TherapyOsteomyelitisPatient ReadmissionReoperationRetrospective StudiesRisk FactorsNPWTPreventionSpine fusionSurgical wound complications

Identifiers

PMID32004742
PMCPMC8063507
OpenAlexW3003766055

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.