Evidence map›Paper›PMID 32004690›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2020

Middle East respiratory syndrome coronavirus (MERS-CoV) - Surveillance and testing in North England from 2012 to 2019.

Hamzah Z Farooq, Emma Davies, Shazaad Ahmad, Nicholas Machin, Louise Hesketh, Malcolm Guiver, Andrew J Turner

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. 2019 Novel coronavirus (COVID-19) overview.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2022
    Article
  4. Review
  5. Review
  6. Advances in vaccine delivery systems against viral infectious diseases.Drug delivery and translational research · 2021
    Review
  7. SARS-CoV-2: Outline, Prevention, and Decontamination.Pathogens (Basel, Switzerland) · 2021
    Review
  8. Article
  9. Middle East Respiratory Syndrome (MERS) and novel coronavirus disease-2019 (COVID-19): From causes to preventions in Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hamzah Z FarooqDepartment of Virology, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Manchester, United Kingdom; Public Health Laboratory Manchester, Manchester, United Kingdom. Electronic address: H.farooq@nhs.net.
Emma DaviesDepartment of Virology, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Public Health Laboratory Manchester, Manchester, United Kingdom.
Shazaad AhmadDepartment of Virology, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Manchester, United Kingdom; Public Health Laboratory Manchester, Manchester, United Kingdom.
Nicholas MachinDepartment of Virology, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Public Health Laboratory Manchester, Manchester, United Kingdom; University of Manchester, Manchester, United Kingdom.
Louise HeskethDepartment of Virology, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Public Health Laboratory Manchester, Manchester, United Kingdom; University of Manchester, Manchester, United Kingdom.
Malcolm GuiverDepartment of Virology, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Public Health Laboratory Manchester, Manchester, United Kingdom; University of Manchester, Manchester, United Kingdom.
Andrew J TurnerDepartment of Virology, Manchester University NHS Foundation Trust, Manchester, United Kingdom; Public Health Laboratory Manchester, Manchester, United Kingdom; University of Manchester, Manchester, United Kingdom.
Manchester University NHS Foundation Trust · GBNorth Manchester General Hospital · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMiddle East respiratory syndrome coronavirus (MERS-CoV) emerged in Saudi Arabia in 2012 and caused an epidemic in the Middle East. Public Health England (PHE) Manchester is one of the two PHE centres in the UK that perform testing for MERS-CoV. The results of the PHE Manchester MERS surveillance from 2012 to 2019 are presented in this report.

methodsRetrospective data were collected for returning travellers from the Middle East fitting the PHE MERS case definition. Respiratory samples were tested for respiratory viruses and MERS-CoV using an in-house RT-PCR assay.

resultsFour hundred and twenty-six (426) samples from 264 patients were tested for MERS Co-V and respiratory viruses. No MERS-CoV infections were identified by PCR. Fifty-six percent of samples were PCR positive for viral or bacterial pathogen with Influenza A as the predominant virus (44%). Sixty-two percent of all patients had a pathogen identified with the highest positivity from sputum samples. Patients with multiple samples demonstrated a 100% diagnostic yield.

conclusionsAlthough no cases of MERS were identified, the majority of patients had Influenza infection for which oseltamivir treatment was indicated and isolation warranted. Sputum samples were the most useful in diagnosing respiratory viruses with a 100% diagnostic yield from patients with multiple samples.

Indexed as

Middle East Respiratory Syndrome CoronavirusTravel-Related IllnessAdolescentAdultAgedAged, 80 and overAntiviral AgentsChildChild, PreschoolCoronavirus InfectionsEnglandEpidemiological MonitoringFemaleHumansInfantInfluenza, HumanAntiviral AgentsOseltamivirEIDEmerging infectious diseaseHCIDHigh consequence infectious diseaseMERSMERS-CoVMiddle East respiratory syndrome coronavirusPublic health epidemiological surveillance

Identifiers

PMID32004690
PMCPMC7129156
OpenAlexW3003664710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.