Evidence map›Paper›PMID 32004465›Full record

ArticleStructure (London, England : 1993)2020

Cryoelectron Microscopy Structure of a Yeast Centromeric Nucleosome at 2.7 Å Resolution.

David Migl, Marc Kschonsak, Christopher P Arthur, Yadana Khin, Stephen C Harrison, Claudio Ciferri, Yoana N Dimitrova

Open access · bronzeAbstract read
In one paragraph

Article in Structure (London, England : 1993), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Histone Variant H2A.Z Enhances Histone and Nucleosome Dynamics.Molecular & cellular proteomics : MCP · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Histone variants and chromatin structure, update of advances.Computational and structural biotechnology journal · 2023
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

David MiglHarvard Medical School, Boston, MA 02115, USA; Biophysics Program, Harvard University, Boston, MA 02115, USA.
Marc KschonsakStructural Biology, Genentech, South San Francisco, CA, USA.
Christopher P ArthurStructural Biology, Genentech, South San Francisco, CA, USA.
Yadana KhinHarvard Medical School, Boston, MA 02115, USA.
Stephen C HarrisonHarvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Boston, MA 02115, USA. Electronic address: harrison@crystal.harvard.edu.
Claudio CiferriStructural Biology, Genentech, South San Francisco, CA, USA. Electronic address: ciferri.claudio@gene.com.
Yoana N DimitrovaStructural Biology, Genentech, South San Francisco, CA, USA. Electronic address: dimitrova.yoana@gene.com.
Harvard University · USGene Therapy Laboratory · FRHoward Hughes Medical Institute · USUniversity of Genoa · IT

Funding

Single particle reconstructionP01GM062580 · NIGMS · HARVARD MEDICAL SCHOOL · PI HARRISON, STEPHEN COPLAN · 2001 to 2016
$23.7M
Howard Hughes Medical InstituteNIGMS NIH HHS P01 GM062580
6 · The paper itself

Abstract

Kinetochores mediate chromosome segregation during cell division. They assemble on centromeric nucleosomes and capture spindle microtubules. In budding yeast, a kinetochore links a single nucleosome, containing the histone variant Cse4

Indexed as

Chromosomal Proteins, Non-HistoneCryoelectron MicroscopyDNA-Binding ProteinsHistonesKinetochoresModels, MolecularNucleosomesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsChromosomal Proteins, Non-HistoneCSE4 protein, S cerevisiaeDNA-Binding ProteinsHistonesNucleosomesSaccharomyces cerevisiae ProteinsCENP-Acryo-EMCse4histoneskinetochoreNCPnucleosomestructure

Identifiers

PMID32004465
PMCPMC7166091
OpenAlexW3003694832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.