ArticleCurrent biology : CB2020
Chromatin Organization in Early Land Plants Reveals an Ancestral Association between H3K27me3, Transposons, and Constitutive Heterochromatin.
Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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107 citing papers in PubMed, 246 citations in OpenAlex.
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- A simple cell-cycle control system in Marchantia polymorpha provides a framework for understanding plant cell proliferation.The Plant cell · 2026Article
- Genome assemblies of the liverwort Blasia pusilla uncover a well-defined pseudoautosomal region on homomorphic UV sex chromosomes.Genome biology · 2026Article
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- MarpolBase: genome database for Marchantia polymorpha featuring high quality reference genome sequences.Plant & cell physiology · 2026Article
- Evolution of a distinct chromatin regulatory landscape in brown algae.Nature ecology & evolution · 2026Article
- Replication timing uncovers a two-compartment nuclear architecture of interphase euchromatin.The Plant cell · 2026Article
- Spatial distribution of isoprenoid enzymes and MpABCG1 transporter influences sesquiterpene accumulation in Marchantia polymorpha oil bodies.Communications biology · 2026Article
- Intermediate evolutionary state of motile sperm and pollen tubes in the extant gymnospermProceedings of the National Academy of Sciences of the United States of America · 2026Article
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- Chromatin state architecture governs transcription factor accessibility across plant genomes.PLoS genetics · 2026Article
- Amyloplasts are necessary for full gravitropism in thallus of Marchantia polymorpha.Journal of experimental botany · 2025Article
- MedakaBase as a unified genomic resource platform for medaka fish biology.DNA research : an international journal for rapid publication of reports on genes and genomes · 2025Article
- Origin and evolutionary trajectories of brown algal sex chromosomes.Nature ecology & evolution · 2025Article
47 more citing papers are in PubMed but not listed here.
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Authors and funding
25 authors at 14 institutions in 9 countries.
Funding
Abstract
Genome packaging by nucleosomes is a hallmark of eukaryotes. Histones and the pathways that deposit, remove, and read histone modifications are deeply conserved. Yet, we lack information regarding chromatin landscapes in extant representatives of ancestors of the main groups of eukaryotes, and our knowledge of the evolution of chromatin-related processes is limited. We used the bryophyte Marchantia polymorpha, which diverged from vascular plants circa 400 mya, to obtain a whole chromosome genome assembly and explore the chromatin landscape and three-dimensional genome organization in an early diverging land plant lineage. Based on genomic profiles of ten chromatin marks, we conclude that the relationship between active marks and gene expression is conserved across land plants. In contrast, we observed distinctive features of transposons and other repetitive sequences in Marchantia compared with flowering plants. Silenced transposons and repeats did not accumulate around centromeres. Although a large fraction of constitutive heterochromatin was marked by H3K9 methylation as in flowering plants, a significant proportion of transposons were marked by H3K27me3, which is otherwise dedicated to the transcriptional repression of protein-coding genes in flowering plants. Chromatin compartmentalization analyses of Hi-C data revealed that repressed B compartments were densely decorated with H3K27me3 but not H3K9 or DNA methylation as reported in flowering plants. We conclude that, in early plants, H3K27me3 played an essential role in heterochromatin function, suggesting an ancestral role of this mark in transposon silencing.
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