ArticleAngewandte Chemie (International ed. in English)2020
Ultra-fast Cycling for Multiplexed Cellular Fluorescence Imaging.
Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Enhanced through-bond energy transfer-based bioorthogonal probe enables catalytic-amplified and sensitive detection of microRNA-21 for clinical lung cancer diagnosis.Smart molecules : open access · 2026Article
- Optically switchable CLEAR probes enable rapid, biocompatible and high-efficiency fluorophore exchange for ultra-plex, high-resolution immunofluorescence imaging.Chemical science · 2026Article
- Single-Cell Protein Assays in Context: From 2D to 3D and In Situ Analysis.Annual review of analytical chemistry (Palo Alto, Calif.) · 2026Review
- Rapid discovery of drug-introduced multiple organ dysfunctionActa pharmaceutica Sinica. B · 2025Article
- Temporal and spatial omics technologies for 4D profiling.Nature methods · 2025Review
- Comprehensive High-Spatial-Resolution Imaging Metabolomics Workflow for Heterogeneous Tissues.Analytical chemistry · 2025Article
- Spatial analysis identifies DC niches as predictors of pembrolizumab therapy in head and neck squamous cell cancer.Cell reports. Medicine · 2025Article
- Review
- Recent Advancements in Subcellular Proteomics: Growing Impact of Organellar Protein Niches on the Understanding of Cell Biology.Journal of proteome research · 2024Review
- Probing the glioma micro-environment: analysis using biopsy in combination with ultra-fast cyclic immunolabeling.bioRxiv : the preprint server for biology · 2024Article
- Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Light-Deactivated Fluorescent Probes (FLASH-Off) for Multiplexed Imaging.Journal of the American Chemical Society · 2023Article
- Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes.Nature biotechnology · 2022Article
- Visualization of living cells and tissues in many colors.Nature biotechnology · 2022Article
- TNIK Inhibition Has Dual Synergistic Effects on Tumor and Associated Immune Cells.Advanced biology · 2022Article
- Single extracellular vesicle analysis for early cancer detection.Trends in molecular medicine · 2022Review
- Multiplexed single-cell analysis of FNA allows accurate diagnosis of salivary gland tumors.Cancer cytopathology · 2022Review
- In Vivo Click Chemistry Enables Multiplexed Intravital Microscopy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Integrated Analytical System for Clinical Single-Cell Analysis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Cyclic microchip assay for measurement of hundreds of functional proteins in single neurons.Nature communications · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Rapid analysis of single and scant cell populations is essential in modern diagnostics, yet existing methods are often limited and slow. Herein, we describe an ultra-fast, highly efficient cycling method for the analysis of single cells based on unique linkers for tetrazine (Tz)/trans-cyclooctene (TCO)-mediated quenching. Surprisingly, the quenching reaction rates were more than 3 orders of magnitude faster (t
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.