Evidence map›Paper›PMID 32004270›Full record

ArticleOptics letters2020

Fiber endface illumination diffuser for endo-cavity photoacoustic imaging.

Hongbo Luo, Guang Yang, Quing Zhu

Abstract read
In one paragraph

Article in Optics letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hongbo Luo
Guang Yang
Quing Zhu

Funding

Near Infrared Diffused Light Imaging with Ultrasound Guidance: Predicting Neoadjuvant Chemotherapy ResponseR01EB002136 · NIBIB · WASHINGTON UNIVERSITY · PI ZHU, QUING · 2003 to 2016
$3.4M
Coregistered Photoacoustic and Ultrasound Imaging for Ovarian Cancer Diagnosis and Risk ManagementR01CA237664 · NCI · WASHINGTON UNIVERSITY · PI POWELL, MATTHEW A, SIEGEL, CARY L · 2020 to 2024
$2.6M
Co-registered photoacoustic and ultrasound imaging for non-invasive ovarian canR01CA151570 · NCI · WASHINGTON UNIVERSITY · PI BREWER, MOLLY A., ZHU, QUING · 2011 to 2015
$1.6M
NCI NIH HHS R01 CA151570NCI NIH HHS R01 CA237664NIBIB NIH HHS R01 EB002136
6 · The paper itself

Abstract

The laser illumination delivery method is important in designing probes that achieve high imaging quality and deep tissue penetration. Here we present a novel, to the best of our knowledge, fiber diffuser tip using microspheres dispersed within an ultraviolet adhesive to scatter light. This diffuser keeps the skin surface fluence under the maximum permissible exposure, while enabling higher laser energy injection to enhance the photoacoustic (PA) signal generated from the tissue. We compare the light diffusion effects of different microsphere materials, sizes, and concentrations, and find that 10 µm silica microspheres provide the best light scattering with minimal 5% output energy loss. With the Zemax simulation and experimental validation, we show that this fiber diffuser tip is a valuable tool for endo-cavity PA imaging.

Identifiers

PMID32004270
PMCPMC7598932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.