ReviewThe Journal of comparative neurology2020
Crosstalk: The diversity of melanopsin ganglion cell types has begun to challenge the canonical divide between image-forming and non-image-forming vision.
Review in The Journal of comparative neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 66 citations in OpenAlex.
- Hominoid-specific calretinin-immunopositivity of the optic radiation (geniculocalcarine tract).Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- Article
- Review
- Expression of Osteopontin in M2 and M4 Intrinsically Photosensitive Retinal Ganglion Cells in the Mouse Retina.Investigative ophthalmology & visual science · 2025Article
- Defining spatial nonuniformities of all ipRGC types using an improved Opn4Cell reports methods · 2024Article
- Flp-recombinase mouse line for genetic manipulation of ipRGCs.bioRxiv : the preprint server for biology · 2024Article
- A newbioRxiv : the preprint server for biology · 2024Article
- Circadian rhythm, ipRGCs, and dopamine signalling in myopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Review
- The cognitive impact of light: illuminating ipRGC circuit mechanisms.Nature reviews. Neuroscience · 2024Review
- A Comprehensive Overview of the Neural Mechanisms of Light Therapy.Neuroscience bulletin · 2024Review
- Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- Melanopsin-mediated optical entrainment regulates circadian rhythms in vertebrates.Communications biology · 2023Review
- Structure, Function, and Molecular Landscapes of the Aging Retina.Annual review of vision science · 2023Review
- Short-term acute bright light exposure induces a prolonged anxiogenic effect in mice via a retinal ipRGC-CeA circuit.Science advances · 2023Article
- A melanopsin ganglion cell subtype forms a dorsal retinal mosaic projecting to the supraoptic nucleus.Nature communications · 2023Article
- A new method to quantify the human visual threshold from melanopsin sensitive ganglion cells.Frontiers in cellular neuroscience · 2023Article
- Retinorecipient areas in the common marmoset (Frontiers in neural circuits · 2023Review
- A review of the current state of research on artificial blue light safety as it applies to digital devices.Heliyon · 2022Review
- The role of ipRGCs in ocular growth and myopia development.Science advances · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Melanopsin ganglion cells have defied convention since their discovery almost 20 years ago. In the years following, many types of these intrinsically photosensitive retinal ganglion cells (ipRGCs) have emerged. In the mouse retina, there are currently six known types (M1-M6) of melanopsin ganglion cells, each with unique morphology, mosaics, connections, physiology, projections, and functions. While melanopsin-expressing cells are usually associated with behaviors like circadian photoentrainment and the pupillary light reflex, the characterization of multiple types has demonstrated a reach that may extend far beyond non-image-forming vision. In fact, studies have shown that individual types of melanopsin ganglion cells have the potential to impact image-forming functions like contrast sensitivity and color opponency. Thus, the goal of this review is to summarize the morphological and functional aspects of the six known types of melanopsin ganglion cells in the mouse retina and to highlight their respective roles in non-image-forming and image-forming vision. Although many melanopsin ganglion cell types do project to image-forming brain targets, it is important to note that this is only the first step in determining their influence on image-forming vision. Even so, the visual system has canonically been divided into these two functional realms and melanopsin ganglion cells have begun to challenge the boundary between them, providing an overlap of visual information that is complementary rather than redundant. Further studies on these ganglion cell photoreceptors will no doubt continue to illustrate an ever-expanding role for melanopsin ganglion cells in image-forming vision.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.