Evidence map›Paper›PMID 32003271›Full record

Observational studyJournal of the American Heart Association2020

Aortic Stiffness and Infarct Healing in Survivors of Acute ST-Segment-Elevation Myocardial Infarction.

Martin Reindl, Christina Tiller, Magdalena Holzknecht, Ivan Lechner, Nicolas Hein, Mathias Pamminger, Benjamin Henninger, Agnes Mayr, Hans-Josef Feistritzer, Gert Klug and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Martin ReindlUniversity Clinic of Internal Medicine III Cardiology and Angiology Medical University of Innsbruck Austria.
Christina TillerUniversity Clinic of Internal Medicine III Cardiology and Angiology Medical University of Innsbruck Austria.
Magdalena HolzknechtUniversity Clinic of Internal Medicine III Cardiology and Angiology Medical University of Innsbruck Austria.
Ivan LechnerUniversity Clinic of Internal Medicine III Cardiology and Angiology Medical University of Innsbruck Austria.
Nicolas HeinUniversity Clinic of Internal Medicine III Cardiology and Angiology Medical University of Innsbruck Austria.
Mathias PammingerUniversity Clinic of Radiology Medical University of Innsbruck Austria.
Benjamin HenningerUniversity Clinic of Radiology Medical University of Innsbruck Austria.
Agnes MayrUniversity Clinic of Radiology Medical University of Innsbruck Austria.
Hans-Josef FeistritzerDepartment of Internal Medicine/Cardiology Heart Center Leipzig at University of Leipzig Germany.
Gert KlugUniversity Clinic of Internal Medicine III Cardiology and Angiology Medical University of Innsbruck Austria.
Axel BauerUniversity Clinic of Internal Medicine III Cardiology and Angiology Medical University of Innsbruck Austria.
Bernhard MetzlerUniversity Clinic of Internal Medicine III Cardiology and Angiology Medical University of Innsbruck Austria.
Sebastian J ReinstadlerUniversity Clinic of Internal Medicine III Cardiology and Angiology Medical University of Innsbruck Austria.
Innsbruck Medical University · ATUniversität Innsbruck · ATLeipzig Heart Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background In survivors of acute ST-segment-elevation myocardial infarction (STEMI), increased aortic stiffness is associated with worse clinical outcome; however, the underlying pathomechanisms are incompletely understood. We aimed to investigate associations between aortic stiffness and infarct healing using comprehensive cardiac magnetic resonance imaging in patients with acute STEMI. Methods and Results This was a prospective observational study including 103 consecutive STEMI patients treated with primary percutaneous coronary intervention. Pulse wave velocity (PWV), the reference standard for aortic stiffness assessment, was determined by a validated phase-contrast cardiac magnetic resonance imaging protocol within the first week after STEMI. Infarct healing, defined as relative infarct size reduction from baseline to 4 months post-STEMI, was determined using late gadolinium-enhanced cardiac magnetic resonance. Median infarct size significantly decreased from 17% of left ventricular mass (interquartile range 9% to 28%) at baseline to 12% (6% to 17%) at 4-month follow-up (

Indexed as

Magnetic Resonance Imaging, CinePercutaneous Coronary InterventionPulse Wave AnalysisVascular StiffnessAgedFemaleHumansMaleMiddle AgedMyocardiumPredictive Value of TestsProspective StudiesST Elevation Myocardial InfarctionTime FactorsTreatment Outcomeaortic stiffnessmagnetic resonance imagingmyocardial delayed enhancementST‐segment–elevation myocardial infarction

Identifiers

PMID32003271
PMCPMC7033867
OpenAlexW3003503107

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.