Evidence map›Paper›PMID 32003253›Full record

ReviewExpert opinion on therapeutic targets2020

Calcitonin gene-related peptide (CGRP): role in migraine pathophysiology and therapeutic targeting.

Anne-Sophie Wattiez, Levi P Sowers, Andrew F Russo

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on therapeutic targets, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 8 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 8 syntheses or guidelines pooled it, 178 citations in OpenAlex.

  1. Efficacy and safety of CGRP monoclonal antibodies for cluster headache: a systematic review and network meta-analysis of randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  8. Exploring the pharmacological action mechanism ofFrontiers in pharmacology · 2022
    Pooled it
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  17. Novel Role for CGRP in Aqueous Humor Outflow.Investigative ophthalmology & visual science · 2026
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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anne-Sophie WattiezDepartment of Physiology and Biophysics, University of Iowa, Iowa City, IA, USA.
Levi P SowersDepartment of Physiology and Biophysics, University of Iowa, Iowa City, IA, USA.
Andrew F RussoDepartment of Physiology and Biophysics, University of Iowa, Iowa City, IA, USA.ORCID 0000-0002-8156-5649
University of Iowa · US

Funding

Perivascular mechanisms of CGRP-induced migraine symptomsR01NS075599 · NINDS · UNIVERSITY OF IOWA · PI RUSSO, ANDREW F · 2011 to 2023
$5.0M
Target validation of a novel CGRP receptor in migraineRF1NS113839 · NINDS · UNIVERSITY OF IOWA · PI HAY, DEBBIE L, RUSSO, ANDREW F · 2019 to 2019
$3.1M
NINDS NIH HHS R01 NS075599NINDS NIH HHS RF1 NS113839
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Molecular Targeted TherapyAnimalsCalcitonin Gene-Related PeptideDrug DevelopmentHumansMigraine DisordersReceptors, Calcitonin Gene-Related PeptideCalcitonin Gene-Related PeptideReceptors, Calcitonin Gene-Related PeptideCGRPgepantsMigrainemonoclonal antibodiestrigeminovascular system

Identifiers

PMID32003253
PMCPMC7050542
OpenAlexW3003841605

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.