Evidence map›Paper›PMID 32002643›Full record

ArticleEuropean radiology2020

Surgically implanted aortic valve bioprostheses deform after implantation: insights from computed tomography.

Marguerite E Faure, Dominika Suchá, Fides R Schwartz, Petr Symersky, Ad J J C Bogers, Jeffrey G Gaca, Lynne M Koweek, Linda M de Heer, Ricardo P J Budde

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Marguerite E FaureDepartment of Radiology and Nuclear Medicine, Erasmus Medical Center, Po Box 2040, 3000, CA, Rotterdam, The Netherlands. m.faure@erasmusmc.nl.ORCID http://orcid.org/0000-0002-5937-6892
Dominika SucháDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Fides R SchwartzDepartment of Radiology, Duke University Medical Center, Durham, USA.
Petr SymerskyDepartment of Cardiothoracic Surgery, VU Medical Center, Amsterdam, The Netherlands.
Ad J J C BogersDepartment of Cardiothoracic Surgery, Erasmus Medical Center, Rotterdam, The Netherlands.
Jeffrey G GacaDepartment of Cardiothoracic Surgery, Duke University Medical Center, Durham, USA.
Lynne M KoweekDepartment of Radiology, Duke University Medical Center, Durham, USA.
Linda M de HeerDepartment of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Ricardo P J BuddeDepartment of Radiology and Nuclear Medicine, Erasmus Medical Center, Po Box 2040, 3000, CA, Rotterdam, The Netherlands.
Duke Medical Center · USErasmus MC · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NLLeiden University Medical Center · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLittle is known about the prevalence and degree of deformation of surgically implanted aortic biological valve prostheses (bio-sAVRs). We assessed bio-sAVR deformation using multidetector-row computed tomography (MDCT).

methodsThree imaging databases were searched for patients with MDCT performed after bio-sAVR implantation. Minimal and maximal valve ring diameters were obtained in systole and/or diastole, depending on the acquired cardiac phase(s). The eccentricity index (EI) was calculated as a measure of deformation as (1 - (minimal diameter/maximal diameter)) × 100%. EI of < 5% was considered none or trivial deformation, 5-10% mild deformation, and > 10% non-circular. Indications for MDCT and implanted valve type were retrieved.

resultsOne hundred fifty-two scans of bio-sAVRs were included. One hundred seventeen measurements were performed in systole and 35 in diastole. None or trivial deformation (EI < 5%) was seen in 67/152 (44%) of patients. Mild deformation (EI 5-10%) was seen in 59/152 (39%) and non-circularity was found in 26/152 (17%) of cases. Overall, median EI was 5.5% (IQR 3.4-7.8). In 77 patients, both systolic and diastolic measurements were performed from the same scan. For these scans, the median EI was 6.5% (IQR 3.4-10.2) in systole and 5.1% (IQR3.1-7.6) in diastole, with a significant difference between both groups (p = 0.006).

conclusionsSurgically implanted aortic biological valve prostheses show mild deformation in 39% of cases and were considered non-circular in 17% of studied valves. KEY POINTS: • Deformation of surgically implanted aortic valve bioprostheses (bio-sAVRs) can be adequately assessed using MDCT. • Bio-sAVRs show at least mild deformation (eccentricity index > 5%) in 56% of studied cases and were considered non-circular (eccentricity index > 10%) in 17% of studied valves. • The higher deformity rate found in bio-sAVRs with (suspected) valve pathology could suggest that geometric deformity may play a role in leaflet malformation and thrombus formation similar to that of transcatheter heart valves.

Indexed as

BioprosthesisHeart Valve ProsthesisAortic ValveDiastoleHeart Valve Prosthesis ImplantationHumansMultidetector Computed TomographyProsthesis FailureSystoleTreatment OutcomeBioprosthesisHeart valve prosthesisMultidetector-row computed tomography

Identifiers

PMID32002643
OpenAlexW3003238138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.