Evidence map›Paper›PMID 32002470›Full record

ArticleEmerging topics in life sciences2019

Provisioning the origin and early evolution of life.

Long-Fei Wu, John D Sutherland

Abstract read
In one paragraph

Article in Emerging topics in life sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Evolution at the Origins of Life?Life (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Synthesis of prebiotic organics from COScientific reports · 2023
    Article
  9. Article
  10. Article
  11. Protometabolism as out-of-equilibrium chemistry.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022
    Review
  12. A Nonenzymatic Analog of Pyrimidine Nucleobase Biosynthesis.Angewandte Chemie (International ed. in English) · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Cyanide at the origin of metabolism.Nature chemistry · 2022
    Article
  17. Article
  18. Article
  19. Chiral Amplification of Phosphoramidates of Amines and Amino Acids in Water.Angewandte Chemie (International ed. in English) · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Long-Fei WuMedical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, U.K.
John D SutherlandMedical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, U.K.

Funding

Medical Research Council MC_UP_A024_1009
6 · The paper itself

Abstract

There is a lot of controversy in the origin and early evolution of life field, but most people agree that at the advent of genetically coded protein synthesis, cells must have had access to ribonucleotides, amino acids, lipids and some sort of energy source. However, the provenance of these materials is a contentious issue - did early life obtain its building blocks prefabricated from the environment, or did it synthesise them from feedstocks such as CO

Identifiers

PMID32002470
PMCPMC6992421

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.