Evidence map›Paper›PMID 32002449›Full record

ArticleBio-protocol2019

Patrick O'Connell, Yong-Hui Zheng, Andrea Amalfitano, Yasser A Aldhamen

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bio-protocol, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Patrick O'ConnellDepartment of Microbiology and Molecular Genetics, College of Osteopathic Medicine, Michigan State University, East Lansing, USA.
Yong-Hui ZhengDepartment of Microbiology and Molecular Genetics, College of Osteopathic Medicine, Michigan State University, East Lansing, USA.
Andrea AmalfitanoDepartment of Microbiology and Molecular Genetics, College of Osteopathic Medicine, Michigan State University, East Lansing, USA.
Yasser A AldhamenDepartment of Microbiology and Molecular Genetics, College of Osteopathic Medicine, Michigan State University, East Lansing, USA.
Michigan State University · USWestern University of Health Sciences · US

Funding

Novel Immunomodulating Therapeutics for HIV-1 TreatmentR21AI122808 · NIAID · MICHIGAN STATE UNIVERSITY · PI ALDHAMEN, YASSER · 2016 to 2017
$410k
NIAID NIH HHS R21 AI122808
6 · The paper itself

Abstract

Monocyte infection by HIV-1 is an important component of chronic HIV pathogenesis. Following infection by HIV-1, monocytes are able to cross the blood brain barrier and set up a viral reservoir in the central nervous system. Additionally, in the setting of chronic HIV-1 infection, monocytes can become activated either directly through HIV-1 infection or indirectly via HIV-1-mediated systemic immune activation. Currently, there are few studies looking at HIV-1 infection of primary human monocytes

Indexed as

FACSFlow cytometryHIVImmunomodulationInfectionMonocytesNeuroinflammationSLAMF7

Identifiers

PMID32002449
PMCPMC6990407
OpenAlexW2954330033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.