Evidence map›Paper›PMID 32002346›Full record

ArticleGlobal spine journal2020

Surgical or Radiation Therapy for the Treatment of Cervical Spine Metastases: Results From the Epidemiology, Process, and Outcomes of Spine Oncology (EPOSO) Cohort.

Michael R Bond, Anne L Versteeg, Arjun Sahgal, Laurence D Rhines, Daniel M Sciubba, James M Schuster, Michael H Weber, Michael G Fehlings, Aron Lazary, Michelle J Clarke and 5 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 5 countries.

Michael R BondUniversity of British Columbia, Vancouver, British Columbia, Canada.
Anne L VersteegUniversity Medical Center Utrecht, Utrecht, Netherlands.
Arjun SahgalSunnybrook Odette Cancer Centre and University of Toronto, Toronto, Ontario, Canada.
Laurence D RhinesThe University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Daniel M SciubbaJohns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0001-7604-434X
James M SchusterHospital of the University of Pennsylvania, Philadelphia, PA, USA.
Michael H WeberMcGill University and Montreal General Hospital, Montreal, Quebec, Canada.
Michael G FehlingsUniversity of Toronto and Toronto Western Hospital, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-5722-6364
Aron LazaryNational Center for Spinal Disorders and Buda Health Center, Budapest, Hungary.
Michelle J ClarkeMayo Clinic, Rochester, MN, USA.
Stefano BorianiIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Chetan BettegowdaJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Paul M ArnoldThe University of Kansas Hospital, Kansas City, Kansas, USA.
Ziya L GokaslanThe Warren Alpert Medical School of Brown University and Rhode Island Hospital and The Miriam Hospital, Providence, RI, USA.
Charles G FisherUniversity of British Columbia, Vancouver, British Columbia, Canada.
Johns Hopkins University · USUniversity of British Columbia · CABrown University · USBuda Health Center · HUHospital of the University of Pennsylvania · USIstituto Ortopedico Galeazzi · ITMayo Clinic in Arizona · USMontreal General Hospital · CASunnybrook Health Science Centre · CAThe University of Kansas Health System · USThe University of Texas MD Anderson Cancer Center · USUniversity Medical Center Utrecht · NLUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designAmbispective cohort study design.

objectivesCervical spine metastases have distinct clinical considerations. The aim of this study was to determine the impact of surgical intervention (± radiotherapy) or radiotherapy alone on health-related quality of life (HRQOL) outcomes in patients treated for cervical metastatic spine tumours.

methodsPatients treated with surgery and/or radiotherapy for cervical spine metastases were identified from the Epidemiology, Process, and Outcomes of Spine Oncology (EPOSO) international multicentre prospective observational study. Demographic, diagnostic, treatment, and HRQOL (numerical rating scale [NRS] pain, EQ-5D (3L), SF-36v2, and SOSGOQ) measures were prospectively collected at baseline, 6 weeks, 3 months, and 6 months postintervention.

resultsFifty-five patients treated for cervical metastases were identified: 38 underwent surgery ± radiation and 17 received radiation alone. Surgically treated patients had higher mean spinal instability neoplastic scores compared with the radiation-alone group (13.0 vs 8.0,

conclusionsSurgically treated cervical metastases patients presented with higher levels of instability, worse baseline pain and HRQOL scores compared with patients who underwent radiotherapy alone. Significant improvements in pain and HRQOL were noted for those patients who received surgical intervention. Limited or no improvements were found in those treated with radiotherapy alone.

Indexed as

cervical metastasesradiotherapyspine oncologysurgery

Identifiers

PMID32002346
PMCPMC6963359
OpenAlexW2934849878

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.