Evidence map›Paper›PMID 32002345›Full record

ArticleGlobal spine journal2020

A Study of Risk Factors for Early-Onset Adjacent Vertebral Fractures After Kyphoplasty.

Masayoshi Morozumi, Yuji Matsubara, Akio Muramoto, Yoshinori Morita, Kei Ando, Kazuyoshi Kobayashi, Masaaki Machino, Kyotaro Ota, Satoshi Tanaka, Shunsuke Kanbara and 3 more

Abstract read
In one paragraph

Article in Global spine journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Efficacy of denosumab versus zoledronate on preventing secondary osteoporotic vertebral compression fracture: a prospective study with 2-year follow-up.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Trial
  3. Article
  4. Development and validation of a prediction model for vertebral recompression and adjacent vertebral fracture after kyphoplasty in geriatric patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Development of risk scoring system for adjacent vertebral fractures after percutaneous vertebroplasty.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  6. Article
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  9. A nomogram for predicting fracture of the sandwich vertebrae after percutaneous vertebral augmentation: a multicenter study with 1-year follow-up.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  10. CT- and MRI-based endplate osteoporosis status assessment for predicting adjacent vertebral fractures after thoracolumbar percutaneous kyphoplasty: a matched comparison study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Masayoshi MorozumiNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.
Yuji MatsubaraKariya Toyota General Hospital, Aichi, Kariya, Japan.
Akio MuramotoKariya Toyota General Hospital, Aichi, Kariya, Japan.
Yoshinori MoritaKariya Toyota General Hospital, Aichi, Kariya, Japan.
Kei AndoNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.
Kazuyoshi KobayashiNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.
Masaaki MachinoNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.
Kyotaro OtaNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.
Satoshi TanakaNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.
Shunsuke KanbaraNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.
Sadayuki ItoNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.
Naoki IshiguroNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.
Shiro ImagamaNagoya University Graduate School of Medicine, Aichi, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective study.

objectivesTo elucidate risk factors for early-onset (2 months after initial kyphoplasty) adjacent vertebral fracture (EO-AVF) after kyphoplasty.

methodsA total of 108 vertebral bodies (95 patients) were included in this study. We examined patient backgrounds, the spinal level of EO-AVFs, surgery-related factors, and imaging findings. We divided the cases into 2 groups: patients with EO-AVF and patients without EO-AVF. Univariate, correlation, and multivariate analyses were conducted to reveal the risks factors for EO-AVFs for these 2 groups.

resultsEO-AVFs developed in 28 vertebral bodies; they did not develop in 80 vertebral bodies. The overall EO-AVF incidence rate was 26%. The spinal level was the thoracolumbar junction for 93% of patients and another level for 7%, thus demonstrating the concentration of EO-AVFs in the thoracolumbar junction. For patients without EO-AVF and those with EO-AVF, there were significant differences in age (76 and 80 years, respectively), preoperative vertebral angles (VAs) (17.8° and 23°, respectively), and corrected VAs (7.3° and 12.7°, respectively). Significant differences were not observed for other factors. Pearson's correlation coefficient was 0.661 (

conclusionAge, preoperative VAs, and corrected VAs are risk factors for EO-AVFs after kyphoplasty.

Indexed as

adjacent fracturecomplicationkyphoplastyminimally invasive surgeryosteoporosis

Identifiers

PMID32002345
PMCPMC6963356

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.