Evidence map›Paper›PMID 32002278›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2019

Paroxysmal Kinesigenic Dyskinesia: First Molecularly Confirmed Case from Africa.

Marieke C J Dekker, Rose Chengo, Happiness H Kumburu, Erik-Jan Kamsteeg, Ben C Hamel

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Marieke C J DekkerDepartment of Paediatrics and Child Health, Kilimanjaro Christian Medical Centre, Moshi, TZ.
Rose ChengoDepartment of Paediatrics and Child Health, Kilimanjaro Christian Medical Centre, Moshi, TZ.
Happiness H KumburuGenomics and Bioinformatics Unit, Kilimanjaro Clinical Research Institute Biotechnology Laboratory, Kilimanjaro Christian Medical Centre, Moshi, TZ.
Erik-Jan KamsteegDepartment of Human Genetics, Radboud University Medical Center, GA Nijmegen, NL.
Ben C HamelDepartment of Human Genetics, Radboud University Medical Center, GA Nijmegen, NL.
Kilimanjaro Christian Medical Centre · TZRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Paroxysmal kinesigenic dyskinesia (PKD) is a movement disorder, with an excellent response to carbamazepine treatment. It has been described in various populations, but not yet in an African population. Case report: In a patient who reported to clinic with side effects of carbamazepine, Discussion: Reporting genetic confirmation of an unusual movement disorder from an equally unusual location shows the wide geographical distribution of PRRT2-associated disease. It also illustrates recognizability of this treatable disorder where the easiest accessible diagnostic tool is neurological history and examination.

Indexed as

AnticonvulsantsCarbamazepineChildDystoniaHumansMaleMembrane ProteinsNerve Tissue ProteinsTanzaniaAnticonvulsantsCarbamazepineMembrane ProteinsNerve Tissue ProteinsPRRT2 protein, humanAfricacarbamazepineParoxysmal Kinesigenic DyskinesiaPRRT2

Identifiers

PMID32002278
PMCPMC6982423
OpenAlexW3004739035

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.