Evidence map›Paper›PMID 32001549›Full record

ArticleeNeuro

Cerebral Contribution to the Execution, But Not Recalibration, of Motor Commands in a Novel Walking Environment.

Digna de Kam, Pablo A Iturralde, Gelsy Torres-Oviedo

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. The Detrimental Effect of Stroke on Motor Adaptation.Neurorehabilitation and neural repair · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Digna de KamSwanson School of Engineering, Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.ORCID 0000-0001-6383-0106
Pablo A IturraldeSwanson School of Engineering, Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213.ORCID 0000-0001-6074-9070
Gelsy Torres-OviedoSwanson School of Engineering, Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 gelsyto@pitt.edu.ORCID 0000-0003-2415-1033
University of Pittsburgh · USRadboud University Nijmegen · NL

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
A computational approach for understanding locomotor learning post-strokeK01NS092785 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TORRES-OVIEDO, GELSY · 2016 to 2018
$673k
NIA NIH HHS P30 AG024827NINDS NIH HHS K01 NS092785
6 · The paper itself

Abstract

Human movements are flexible as they continuously adapt to changes in the environment. The recalibration of corrective responses to sustained perturbations (e.g., constant force) altering one's movement contributes to this flexibility. We asked whether the recalibration of corrective actions involve cerebral structures using stroke as a disease model. We characterized changes in muscle activity in stroke survivors and control subjects before, during, and after walking on a split-belt treadmill moving the legs at different speeds. The recalibration of corrective muscle activity was comparable between stroke survivors and control subjects, which was unexpected given the known deficits in feedback responses poststroke. Also, the intact recalibration in stroke survivors contrasted their limited ability to adjust their muscle activity during steady-state split-belt walking. Our results suggest that the recalibration and execution of motor commands are partially dissociable: cerebral lesions interfere with the execution, but not the recalibration, of motor commands on novel movement demands.

Indexed as

StrokeWalkingAdaptation, PhysiologicalExercise TestHumansLegelectromyographyfeedbacksensorimotor adaptationsplit-beltstroke

Identifiers

PMID32001549
PMCPMC7053171
OpenAlexW3003395424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.