ArticleAJNR. American journal of neuroradiology2020
Delayed Leukoencephalopathy: A Rare Complication after Coiling of Cerebral Aneurysms.
Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Outcomes, complications, and management in flow diverter treatment of cerebral aneurysms: a 15-year single-center experience.Neuroradiology · 2026Article
- Damage to Polymer Coatings on Microguidewire Tips through Shaping and J-wiring for Optimizing Flow Diverter Deployment: A Scanning Electron Microscopy Study.Neurointervention · 2026Article
- Delayed non ischemic cerebral enhancing lesions after endovascular stent assisted coiling of an unruptured intracranial aneurysm, a case description followed by a literature analysis on the probable causes, differential diagnosis and treatment.Quantitative imaging in medicine and surgery · 2025Article
- Cerebral foreign body reaction (CFBR) after endovascular treatments is a rare event to be aware of: case series and review of literature.Journal of neurology · 2025Review
- Long-term follow-up of patients with non-ischemic cerebral enhancing lesions following endovascular aneurysm treatment: magnetic resonance imaging findings, clinical course, and treatment.Therapeutic advances in neurological disorders · 2025Article
- Non-ischemic cerebral enhancing (NICE) lesions after flow diversion for intracranial aneurysms: a multicenter study.Journal of neurointerventional surgery · 2024Article
- Possible Occurrence of Delayed Leukoencephalopathy Following Acute Ischemic Stroke With Large-Vessel Occlusion.Stroke (Hoboken, N.J.) · 2024Article
- Delayed Leucoencephalopathy as a Complication after Endovascular Therapy of Intracranial Aneurysms-A Case Series.Journal of clinical medicine · 2023Article
- Reversible and multiphasic parenchymal changes in MRI after coil embolization for a ruptured cerebral aneurysm.Surgical neurology international · 2023Article
- Incidence, clinical spectrum, and immunotherapy of non-ischemic cerebral enhancing lesions after endovascular therapy.Therapeutic advances in neurological disorders · 2022Article
- Incidence and Risk Factors for Acute Transient Contrast-Induced Neurologic Deficit: A Systematic Review With Meta-Analysis.Stroke (Hoboken, N.J.) · 2022Article
- Delayed leukoencephalopathy from suspected polymer embolism after neuroendovascular procedures.The neuroradiology journal · 2021Review
- Delayed Leukoencephalopathy and Foreign Body Reaction After Endovascular Treatment in Patients With Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage-A Systematic Review of the Literature.Frontiers in surgery · 2021Article
- Microcatheter Originating Debris during Neuroendovascular Procedures: Mechanism of Dislodgement and Its Prevention.AJNR. American journal of neuroradiology · 2020Article
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Authors and funding
8 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeDelayed leukoencephalopathy is a rare complication that occurs after endovascular coiling of cerebral aneurysms. We aimed to describe a clinical picture of delayed leukoencephalopathy and explore potential associations with procedural characteristics. MATERIALS AND
methodsWe considered endovascular coiling procedures for cerebral aneurysms performed between January 2006 and December 2017 in our institution with follow-up MRIs. We used logistic regression models to estimate the ORs of delayed leukoencephalopathy for each procedural characteristic.
resultsWe reviewed 1754 endovascular coiling procedures of 1594 aneurysms. Sixteen of 1722 (0.9%) procedures demonstrated delayed leukoencephalopathy on follow-up FLAIR MR imaging examinations after a median period of 71.5 days (interquartile range, 30-101 days) in the form of high-signal changes in the white matter at locations remote from the coil mass. Seven patients had headaches or hemiparesis, and 9 patients were asymptomatic. All imaging-associated changes improved subsequently. We found indications suggesting an association between delayed leukoencephalopathy and the number of microcatheters used per procedure (
conclusionsDelayed leukoencephalopathy after coiling of cerebral aneurysms may have multiple etiologies such as foreign body emboli, contrast-induced encephalopathy, or hypersensitivity reaction to foreign bodies.
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