ArticleNeuron2020
Neural Correlates of Reinforcement Learning in Mid-lateral Cerebellum.
Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 57 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed.
- Predictive and instructive cerebellar encoding of dopamine reward drives motivated behavior.Nature neuroscience · 2026Article
- Unsupervised nonmotor learning in the human cerebellum.bioRxiv : the preprint server for biology · 2026Article
- Cerebellar neural populations orchestrate dopamine reward signaling with single-trial precision.Nature communications · 2026Article
- The Human Cerebellum Encodes Temporally Sensitive Reinforcement Learning Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Impulsivity in cerebellar ataxia: an online, multidimensional assessment.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Consensus Paper: Models of Cerebellar Functions.Cerebellum (London, England) · 2026Review
- Comparison of Signals from Cerebellar Purkinje Cells and Deep Nuclei during Temporal Prediction in Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Brain-Behavior Relationships: Neural Mechanisms of Impulsivity and Compulsivity in Neuropsychiatric Disorders.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2025Review
- Neural correlates of trial outcome monitoring during long-term learning in primate posterior parietal cortex.Nature communications · 2025Article
- Sustained visual signals in the primate cerebellar dentate nucleus drive associative learning.Communications biology · 2025Article
- Stage-dependent cerebrocerebellar communication during sensorimotor processing.Nature communications · 2025Article
- The human cerebellum encodes temporally sensitive reinforcement learning signals.bioRxiv : the preprint server for biology · 2025Article
- Platform Technology for Extended Reality Biofeedback Training Under Operant Conditioning for Functional Limb Weakness: Protocol for the Coproduction of an at-Home Solution (React2Home).JMIR research protocols · 2025Article
- A cerebello-thalamo-cortical pathway transmits reward-based post-error signals for motor timing correction during learning in male mice.Nature communications · 2025Article
- Synergistic Reinforcement Learning by Cooperation of the Cerebellum and Basal Ganglia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Emergent Aspects of the Integration of Sensory and Motor Functions.Brain sciences · 2025Review
- Social and emotional learning in the cerebellum.Nature reviews. Neuroscience · 2024Review
- The Role of the Cerebellum in Learning to Predict Reward: Evidence from Cerebellar Ataxia.Cerebellum (London, England) · 2024Article
- Reduced sensitivity to future consequences underlies gambling decision in cerebellar ataxia.Journal of the neurological sciences · 2024Article
- A cerebro-cerebellar network for learning visuomotor associations.Nature communications · 2024Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
4 authors.
Funding
Abstract
The role of the cerebellum in non-motor learning is poorly understood. Here, we investigated the activity of Purkinje cells (P-cells) in the mid-lateral cerebellum as the monkey learned to associate one arbitrary symbol with the movement of the left hand and another with the movement of the right hand. During learning, but not when the monkey had learned the association, the simple spike responses of P-cells reported the outcome of the animal's most recent decision without concomitant changes in other sensorimotor parameters such as hand movement, licking, or eye movement. At the population level, P-cells collectively maintained a memory of the most recent decision throughout the entire trial. As the monkeys learned the association, the magnitude of this reward-related error signal approached zero. Our results provide a major departure from the current understanding of cerebellar processing and have critical implications for cerebellum's role in cognitive control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.