Evidence map›Paper›PMID 32000833›Full record

ArticleRadiation oncology (London, England)2020

Survey of current practices from an international task force for gynecological stereotactic ablative radiotherapy.

E Leung, A Gladwish, A Sahgal, S S Lo, C A Kunos, R M Lanciano, C A Mantz, M Guckenberger, T M Zagar, N A Mayr and 5 more

Open access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Spanish Society for Radiation Oncology and Spanish Society of Medical Physicists recommendations on reirradiation in gynecological cancer: reirradiation techniques, survival outcomes, dose, and toxicity.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Guideline
  2. Trial
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 5 countries.

E LeungDepartment of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. eric.leung@sunnybrook.ca.
A GladwishRoyal Victoria Hospital, Barrie, ON, Canada.
A SahgalDepartment of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
S S LoDepartment of Radiation Oncology, University of Washington, Seattle, WA, USA.
C A KunosNational Cancer Institute, Rockville, MD, USA.
R M LancianoDelaware County Memorial Hospital/Philadelphia Cyberknife, Drexel Hill, PA, USA.
C A Mantz21st Century Oncology, Fort Myers, FL, USA.
M GuckenbergerUniversity Hospital Zuerich, Zuerich, Switzerland.
T M ZagarNortheastern Radiation Oncology, Glen Falls, NY, USA.
N A MayrDepartment of Radiation Oncology, University of Washington, Seattle, WA, USA.
A R ChangSoonchunhyang University Seoul Hospital, Seoul, South Korea.
S JorcanoInstituto Oncologico Teknon, Barcelona, Spain.
T BiswasCase Western Reserve University School of Medicine, Cleveland, OH, USA.
A PontorieroUniversity of Messina, Messina, Italy.
K V AlbuquerqueUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Sunnybrook Health Science Centre · CAUniversity of Washington · US21st Century Oncology (United States) · USCase Western Reserve University · USDelaware County Memorial Hospital · USHospital Quirón Teknon · ESNational Cancer Institute · USNortheast Radiation Oncology Center · USRoyal Victoria Regional Health Centre · CASoonchunhyang University Hospital · KRThe University of Texas Southwestern Medical Center · USUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStereotactic Ablative Radiotherapy (SABR) is an effective treatment that improves local control for many tumours. However, the role of SABR in gynecological cancers (GYN) has not been well-established. We hypothesize that there exists considerable variation in GYN-SABR practice and technique. The goal of this study is to describe clinical and technical factors in utilization of GYN-SABR among 11 experienced radiation oncologists. MATERIALS AND

methodsA 63 question survey on GYN-SABR was sent to 11 radiation oncologists (5 countries) who have published original research, conducted trials or have an established program at their institutions. Responses were combined and analyzed at a central institution.

resultsMost respondents indicated that salvage therapy (non-irradiated or re-irradiated field) for nodal (81%) and primary recurrent disease (91%) could be considered standard options for SABR in the setting of inability to administer brachytherapy. All other indications should be considered on clinical trials. Most would not offer SABR as a boost in primary treatment off-trial without absolute contraindications to brachytherapy. Multi-modality imaging is often (91%) used for planning including PET, CT contrast and MRI. There is a wide variation for OAR tolerances however small bowel is considered the dose-limiting structure for most experts (91%). Fractionation schedules range from 3 to 6 fractions for nodal/primary definitive and boost SABR.

conclusionsAlthough SABR has become increasingly standard in other oncology disease sites, there remains a wide variation in both clinical and technical factors when treating GYN cancers. Nodal and recurrent disease is considered a potential indication for SABR whereas other indications should be offered on clinical trials. This study summarizes SABR practices among GYN radiation oncologists while further studies are needed to establish consensus guidelines for GYN-SABR treatment.

Indexed as

Dose Fractionation, RadiationFemaleGenital Neoplasms, FemaleHumansLymphatic MetastasisMultimodal ImagingNeoplasm Recurrence, LocalOrgans at RiskPractice Patterns, Physicians'Radiation OncologistsRadiosurgeryRadiotherapy Planning, Computer-AssistedSalvage TherapySurveys and QuestionnairesConsensusGynecologicalRadiationSABRSBRTStereotactic

Identifiers

PMID32000833
PMCPMC6993370
OpenAlexW3004543269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.