ArticleBMC infectious diseases2020
Pulmonary Cryptococcosis: comparison of Cryptococcal antigen detection and radiography in Immunocompetent and Immunocompromised patients.
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Diagnostic performance of the IMMY cryptococcal antigen lateral flow assay on serum and cerebrospinal fluid for diagnosis of cryptococcosis in HIV-negative patients: a systematic review.BMC infectious diseases · 2023Pooled it
- Comparison of the clinical manifestations and chest CT findings of pulmonary cryptococcosis in immunocompetent and immunocompromised patients: a systematic review and meta-analysis.BMC pulmonary medicine · 2022Pooled it
- The Diagnostic Challenge in Pulmonary Cryptococcosis Among Immunocompetent Patients: The 'False-Negative' Serum Cryptococcal Antigen.Journal of fungi (Basel, Switzerland) · 2026Article
- Pulmonary cryptococcosis in routine care: the clinical-radiologic spectrum and transparent evidence-tier reporting (confirmed versus presumed) among patients with no recorded immunocompromising conditions.Journal of medical microbiology · 2026Observational
- Pulmonary cryptococcosis beyond human immunodeficiency virus: a five-year cohort study of diagnostic challenges, radiologic mimics, and clinical predictors.Journal of thoracic disease · 2026Article
- Evaluating the diagnostic efficacy of metagenomic next-generation sequencing in bronchoalveolar lavage fluid for pulmonary cryptococcosis with different clinical and imaging characteristics.BMC infectious diseases · 2025Article
- Clinical-imaging and therapeutic evaluation of nodule-mass pulmonary cryptococcosis and pneumonia-type pulmonary cryptococcosis.BMC pulmonary medicine · 2025Article
- Pulmonary cryptococcosis in immunocompetent children presenting with chest pain: Three case reports.World journal of clinical cases · 2025Article
- A rare case of disseminated pulmonary cryptococcosis in an immunocompetent patient.BMC pulmonary medicine · 2024Article
- Lung adenocarcinoma concurrent with pulmonary cryptococcosis: a case report and literature review.BMC pulmonary medicine · 2024Review
- Clinical, radiological, and laboratory features of HIV-negative pulmonary cryptococcosis with regard to serum lateral flow assay.Frontiers in medicine · 2024Article
- Finger-Prick Whole Blood Cryptococcal Antigen Lateral Flow Assay for the Diagnosis of Cryptococcosis in HIV-Negative Patients: A Case Series Study in Two Tertiary Centers in São Paulo, Brazil.Journal of fungi (Basel, Switzerland) · 2023Article
- Comparison of different therapeutic approaches for pulmonary cryptococcosis in kidney transplant recipients: a 15-year retrospective analysis.Frontiers in medicine · 2023Article
- Clinicoradiological Features of Pulmonary Cryptococcosis in Immunocompetent Patients.Journal of the Korean Society of Radiology · 2023Article
- Comparison of CT findings and histopathological characteristics of pulmonary cryptococcosis in immunocompetent and immunocompromised patients.Scientific reports · 2022Article
- Metagenomic next-generation sequencing assists in the diagnosis ofFrontiers in public health · 2022Review
- Clinical features of cryptococcosis in patients with different immune statuses: a multicenter study in Jiangsu Province-China.BMC infectious diseases · 2021Article
- [Case Report: Three Pediatric Pulmonary Cryptococcosis Patients with Prominent Manifestation of Mediastinal Lymphadenopathy].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2021Article
- Comprehensive Analysis and Risk Identification of Pulmonary Cryptococcosis in Non-HIV Patients.Journal of fungi (Basel, Switzerland) · 2021Article
- Development and Application of Rapid Clinical Visualization Molecular Diagnostic Technology forFrontiers in cellular and infection microbiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundWe compared the cryptococcal antigen detection and imaging findings between immunocompetent and immunocompromised patients in whom pulmonary cryptococcosis had been diagnosed. The aim of our study was to determine whether the patient's immune status and radiography affect the detection of cryptococcal antigen.
methodsAccording to whether they took immunosuppressive drugs or not, seventy and eight adult patients with pulmonary cryptococcosis were divided into two groups: the immunocompetent group and the immunocompromised group. According to the detection of CrAg, each group was divided into the CrAg+ group and the CrAg- group. Then, clinical records, laboratory examinations and computed tomography findings were collected and analyzed.
resultsNo difference was found in baseline characteristics, clinical symptoms, and laboratory investigations. By comparing CrAg detection in these two groups, it was found that the number of CrAg+ cases in the immunocompetent group was more than that in the immunocompromised group. And in the immunocompetent group, diffuse lesions were more common in CrAg+ group and limited lesions were more frequently observed in CrAg- group.
conclusionsThe patient's immune status and radiography would affect the detection of cryptococcal antigen. And serum CrAg could be a useful tool for the diagnosis of pulmonary cryptococcosis in immunocompetent patients with extensive lung involvement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.