Evidence map›Paper›PMID 32000678›Full record

Observational studyBMC cardiovascular disorders2020

Impact of glycemic control status on patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention.

Yan Li, Xiaowen Li, Yinhua Zhang, Leimin Zhang, Qingqing Wu, Zhaorun Bai, Jin Si, Xuebing Zuo, Ning Shi, Jing Li and 1 more

Open access · goldAbstract readComparative StudyObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yan LiDepartent of Cardiology, Xuanwu hospital, Capital Medical University, Beijing, China.
Xiaowen LiEmergency Department, Aerospace Center Hospital, Beijing, China.
Yinhua ZhangDepartent of Cardiology, Xuanwu hospital, Capital Medical University, Beijing, China.
Leimin ZhangDepartment of internal medicine, Qinghe Substation Hospital of Beijing Municipal Administration of Prisons, Beijing, China.
Qingqing WuDepartment of Cardiology, Beijing Luhe Hospital, Capital Medical University, Beijing, China.
Zhaorun BaiDepartent of Cardiology, Xuanwu hospital, Capital Medical University, Beijing, China.
Jin SiDepartent of Cardiology, Xuanwu hospital, Capital Medical University, Beijing, China.
Xuebing ZuoDepartent of Cardiology, Xuanwu hospital, Capital Medical University, Beijing, China.
Ning ShiDepartent of Cardiology, Xuanwu hospital, Capital Medical University, Beijing, China.
Jing LiDepartent of Cardiology, Xuanwu hospital, Capital Medical University, Beijing, China. shpxbb@sina.com.
Xi ChuHealth Management Center, Xuanwu hospital, Capital Medical University, Beijing, China. cissy9007@163.com.
Capital Medical University · CNAerospace Center Hospital · CNBeijing Luhe Hospital Affiliated to Capital Medical University · CNBeijing Municipal Administration of Hospitals · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe combined effects of diabetes mellitus (DM), admission plasma glucose (APG), and glycated hemoglobin (HbA1c) levels on predicting long-term clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) are unknown. Therefore, we evaluated their combined effects on long-term clinical outcomes in STEMI patients treated with pPCI.

methodsIn total, 350 consecutive patients with STEMI undergoing pPCI were enrolled. Patients were divided into 3 groups according to DM history and APG and HbA1c levels. The cumulative rates of 24-month all-cause deaths and major adverse cardiac and cerebrovascular events (MACCEs) were calculated.

resultsBoth the incidence of all-cause deaths and cumulative rates of MACCEs were significantly the lowest in patients without a DM history and admission HbA1c level < 6.5%. DM patients with poor glycemic control or stress hyperglycemia on admission experienced the highest rates of all-cause deaths, MACCEs, and cardiac deaths. Admission HbA1c levels, Triglyceride (TG) levels, hemoglobin levels, DM history, and admission Killip class > 1 correlated with 24-month all-cause death; HbA1c levels on admission, DM history, APG levels, history of stroke, history of coronary heart disease, and TG levels on admission were significantly associated with MACCEs through the 24-month follow-up. The predictive effects of combining DM and APG and HbA1c levels were such that for STEMI patients undergoing pPCI, DM patients with poor glycemic control or with stress hyperglycemia on admission had worse prognosis than other patients.

conclusionStrict control of glycemic status may improve the survival of patients who have both DM and coronary heart diseases.

Indexed as

Percutaneous Coronary InterventionAgedBiomarkersBlood GlucoseCause of DeathCoronary Artery DiseaseDiabetes MellitusFemaleGlycated HemoglobinHumansHyperglycemiaMaleMiddle AgedPatient AdmissionRetrospective StudiesRisk AssessmentBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanDiabetesGlycated hemoglobinHyperglycemiaPercutaneous coronary interventionST-segment elevation myocardial infarction

Identifiers

PMID32000678
PMCPMC6993353
OpenAlexW3013725236

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.