Evidence map›Paper›PMID 32000661›Full record

ArticleBMC genomics2020

ASlive: a database for alternative splicing atlas in livestock animals.

Jinding Liu, Suxu Tan, Shuiqing Huang, Wen Huang

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Functional analysis of theAnimal biotechnology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jinding LiuCollege of Information Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China.
Suxu TanDepartment of Animal Science, Michigan State University, East Lansing, MI, 48824, USA.
Shuiqing HuangCollege of Information Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China. sqhuang@njau.edu.cn.
Wen HuangDepartment of Animal Science, Michigan State University, East Lansing, MI, 48824, USA. huangw53@msu.edu.ORCID http://orcid.org/0000-0001-6788-8364
Michigan State University · USNanjing Agricultural University · CN

Funding

Michigan State University NANanjing Agricultural University NA
6 · The paper itself

Abstract

backgroundAlternative splicing is an important biological process whose precision must be tightly regulated during growth and development. Although there are species, disease (e.g. cancers), or study specific databases available in many organisms, no database exists in livestock animals specifically tailored for alternative splicing. DESCRIPTION: We present in this study the development and implementation of a database for alternative splicing atlas in livestock animals (ASlive.org). Using publicly available RNASeq data sets across many tissues, cell types, and biological conditions totaling 28.6 T bases, we built a database of alternative splicing events in five major livestock and poultry animal species (cattle, sheep, pigs, horses, and chickens). The database contains many types of information on alternative splicing events, including basic information such as genomic locations, genes, and event types, quantitative measurements of alternative splicing in the form of percent spliced in (PSI), overlap with known DNA variants, as well as orthologous events across different lineage groups.

conclusionsThis database, the first of its kind in livestock animals, will provide a useful exploratory tool to assist functional annotation of animal genomes.

Indexed as

Alternative SplicingDatabases, GeneticAnimalsCattleHorsesLivestockSequence AlignmentSequence Analysis, RNASheepSwine

Identifiers

PMID32000661
PMCPMC6993437
OpenAlexW3013032384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.