Evidence map›Paper›PMID 32000456›Full record

ArticleMedicine2020

Heparin-free veno-venous extracorporeal membrane oxygenation in a multiple trauma patient: A case report.

Youn Young Lee, Hee Jung Baik, Heeseung Lee, Chi Hyo Kim, Rack Kyung Chung, Jong In Han, Hyunyoung Joo, Jae Hee Woo

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06868823 (LMWH Versus UFH as ECMO Anticoagulation in Lung Transplantation), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06868823 recruitingnot on this mapstarted 2025, after this paper: background citation

LMWH Versus UFH as ECMO Anticoagulation in Lung Transplantation: A Prospective, Observational, and Pilot Study

TypeobservationalSponsorUniversity Hospital, MotolRan2025 to 2025Enrolled40ConditionsLung Transplantation, Extracorporeal Membrane Oxygenation (ECMO), Anticoagulants and Bleeding Disorders
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Veno-arterial-venous extracorporal membrane oxygenation (V-AV ECMO) in a patient in ARDS and cardiac instability after severe polytrauma.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2024
    Article
  5. Review
  6. Basics of Extracorporeal Membrane Oxygenation.The Surgical clinics of North America · 2022
    Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Youn Young LeeDepartment of Anesthesiology and Pain Medicine, Ewha Womans University Hospital.
Hee Jung BaikDepartment of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Seoul, South Korea.
Heeseung LeeDepartment of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Seoul, South Korea.
Chi Hyo KimDepartment of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Seoul, South Korea.
Rack Kyung ChungDepartment of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Seoul, South Korea.
Jong In HanDepartment of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Seoul, South Korea.
Hyunyoung JooDepartment of Anesthesiology and Pain Medicine, Ewha Womans University Hospital.
Jae Hee WooDepartment of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Seoul, South Korea.
Ewha Womans University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleExtracorporeal membrane oxygenation (ECMO) in multiple trauma patients with post-traumatic respiratory failure can be quite challenging because of the need for systemic anticoagulation, which may lead to excessive bleeding. In the last decade, there is a growing body of evidence that veno-venous ECMO (VV-ECMO) is lifesaving in multiple trauma patients with acute respiratory distress syndrome, thanks to technical improvements in ECMO devices. PATIENT CONCERNS: We report a case of a 17-year-old multiple trauma patient who was drunken and had confused mentality. DIAGNOSES: She was suffered from critical respiratory failure (life-threatening hypoxemia and severe hypercapnia/acidosis lasting for 70 minutes) accompanied by cardiac arrest and trauma-induced coagulopathy during general anesthesia.

interventionsWe decided to start heparin-free VV-ECMO after cardiac arrest considering risk of hemorrhage. OUTCOMES: She survived with no neurologic sequelae after immediate treatment with heparin-free VV-ECMO. LESSONS: Heparin-free VV-ECMO can be used as a resuscitative therapy in multiple trauma patients with critical respiratory failure accompanied by coagulopathy. Even in cases in which life-threatening hypoxemia and severe hypercapnia/acidosis last for >1 hours during CPR for cardiac arrest, VV-ECMO could be considered a potential lifesaving treatment.

Indexed as

AdolescentBlood Coagulation DisordersExtracorporeal Membrane OxygenationFemaleHeart ArrestHumansMultiple TraumaRespiratory Distress Syndrome

Identifiers

PMID32000456
PMCPMC7004685
OpenAlexW3003209575

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.