ArticleMedicine2020
Primary anorectal malignant melanoma: A case report.
Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Primary Anorectal Melanoma: A Case Report.JNMA; journal of the Nepal Medical Association · 2023Article
- Metastatic Anorectal Melanoma Presenting as Seizures: An Infrequent Culprit.Diseases (Basel, Switzerland) · 2022Article
- Hematochezia in Patient with Rectal Tumor: Consideration of Various Diagnostic Possibilities.Clinical endoscopy · 2021Article
- 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Evaluation of Anorectal Malignant Melanoma: A Case Series.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAnorectal malignant melanoma (AMM) is a rare and aggressive malignance with poor prognosis, yet no consensus of treatment exists to date. Abdominoperineal resection surgery (APR) is the standard treatment of anorectal malignant melanoma, capable of controlling lymphatic spread and obtaining a large negative margin for local control but it can lead to complications. Wide local excision (WLE) allows for quicker recovery and has minimal impact on bowel function (i.e., bypassing the need for a stoma). PATIENT CONCERNS: A 66-year-old male patient presented with a 2-months history of painless rectal bleeding. DIAGNOSIS: The characteristic finding from colonoscopy and magnetic resonance imaging led to a diagnosis of colorectal cancer. Immunohistochemistry analyses confirmed malignant melanoma. The tumor was classified as: HMB-45(+), S-100(+), CD117(±), PCK(-), ki-67(+, 10%).
interventionsThe patient underwent abdominoperineal resection with no other adjuvant therapy. OUTCOMES: The patient is doing well at 24 month after the operation, with no signs of recurrence.
conclusionAMM is a rare malignance, and is easy to misdiagnose. The therapy approach remains controversial. Every effort should be made to ensure prompt diagnosis and to define the optimally effective standard therapy approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.