Evidence map›Paper›PMID 31999995›Full record

ArticleEnvironmental research2020

Exposure to ambient air pollution and early childhood behavior: A longitudinal cohort study.

Christine T Loftus, Yu Ni, Adam A Szpiro, Marnie F Hazlehurst, Frances A Tylavsky, Nicole R Bush, Sheela Sathyanarayana, Kecia N Carroll, Michael Young, Catherine J Karr and 1 more

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 62 citations in OpenAlex.

  1. Trial
  2. Review
  3. Revisiting 'environmental effects': Directions for multidisciplinary investigations of air quality and psychopathology.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Review
  13. Review
  14. Article
  15. Prenatal PMToxics · 2024
    Review
  16. Article
  17. Article
  18. A model for rapid PMGeoscientific model development · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Christine T LoftusDepartment of Environmental and Occupational Health Sciences, 4225 Roosevelt Way NE, University of Washington (UW), Seattle, WA, 95105, USA. Electronic address: cloftus@uw.edu.
Yu NiDepartment of Epidemiology, 1959 NE Pacific Street, Box 357236, UW, Seattle, WA, 98195, USA.
Adam A SzpiroDepartment of Biostatistics, UW, Box 357232, Seattle, WA, 98195, USA.
Marnie F HazlehurstDepartment of Epidemiology, 1959 NE Pacific Street, Box 357236, UW, Seattle, WA, 98195, USA.
Frances A TylavskyDepartment of Biostatistics and Epidemiology, 462 Doctors Office Building, 66 N Pauline St, University of Tennessee Health Science Center, Memphis, TN, 38163, USA.
Nicole R BushDepartment of Psychiatry, University of California (UC), 401 Parnassus Ave, San Francisco, CA, 94143, USA; Department of Pediatrics, 550 16th Street, Box 0110, UC, San Francisco, CA, 94143, USA.
Sheela SathyanarayanaDepartment of Environmental and Occupational Health Sciences, 4225 Roosevelt Way NE, University of Washington (UW), Seattle, WA, 95105, USA; Seattle Children's Research Institute, 1900 9th Ave, Seattle, WA, 98101, USA; Department of Pediatrics, 1959 NE Pacific St, UW, Seattle, WA, 98195, USA.
Kecia N CarrollDivision of General Pediatrics, 2200 Children's Way, Vanderbilt University Medical Center, Nashville, TN, 27232, USA.
Michael YoungDepartment of Environmental and Occupational Health Sciences, 4225 Roosevelt Way NE, University of Washington (UW), Seattle, WA, 95105, USA.
Catherine J KarrDepartment of Environmental and Occupational Health Sciences, 4225 Roosevelt Way NE, University of Washington (UW), Seattle, WA, 95105, USA; Department of Epidemiology, 1959 NE Pacific Street, Box 357236, UW, Seattle, WA, 98195, USA; Department of Pediatrics, 1959 NE Pacific St, UW, Seattle, WA, 98195, USA.
Kaja Z LeWinnDepartment of Psychiatry, University of California (UC), 401 Parnassus Ave, San Francisco, CA, 94143, USA.
University of California, San Francisco · USUniversity of Washington · USSeattle Pacific University · USTheodore Roosevelt High School · USUniversity of Tennessee Health Science Center · USVanderbilt University Medical Center · US

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI ALI SHOJAIE · 1995 to 2026
$42.5M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUG3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2016 to 2017
$5.1M
Pregnancy Folate Status & Early Childhood Respiratory & Atopic Disease OutcomesR01HL109977 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CARROLL, KECIA NICOLE · 2011 to 2015
$3.4M
NHLBI NIH HHS R01 HL109977NIEHS NIH HHS P30 ES007033NIH HHS UG3 OD023271NIH HHS UH3 OD023271
6 · The paper itself

Abstract

backgroundPrenatal and early life air pollution exposure may impair healthy neurodevelopment, increasing risk of childhood behavioral disorders, but epidemiological evidence is inconsistent. Little is known about factors that determine susceptibility.

methodsParticipants were mother-child dyads from the CANDLE study, an ECHO PATHWAYS Consortium birth cohort set in the mid-South United States, who completed a preschool visit. We estimated prenatal and childhood exposures to nitrogen dioxide (NO

resultsThe analytic sample (N = 975 of 1503 enrolled) was 64% African American and 53% had a household annual income below $35,000; child mean age was 4.3 years (SD: 0.4). Mean prenatal NO

conclusionsFindings showed that air pollution exposure is positively associated with child behavior problems and that African American and low SES children may be more susceptible. Importantly, associations were observed at exposures below current air quality standards.

Indexed as

Air PollutantsAir PollutionChild BehaviorChild, PreschoolEnvironmental ExposureFemaleHumansLongitudinal StudiesNitrogen DioxideParticulate MatterPregnancyAir PollutantsNitrogen DioxideParticulate MatterAir pollutionEpidemiologyLongitudinal cohortNeurodevelopmentPediatric health

Identifiers

PMID31999995
PMCPMC8903039
OpenAlexW2994670641

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.