Evidence map›Paper›PMID 31999899›Full record

ArticleChronic obstructive pulmonary diseases (Miami, Fla.)2020

Short Physical Performance Battery: What Does Each Sub-Test Measure in Patients with Chronic Obstructive Pulmonary Disease?

Divya Mohan, Victoria S Benson, Matthew Allinder, Nicholas Galwey, Charlotte E Bolton, John R Cockcroft, William MacNee, Ian B Wilkinson, Ruth Tal-Singer, Michael I Polkey and 1 more

Abstract read
In one paragraph

Article in Chronic obstructive pulmonary diseases (Miami, Fla.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Virtual Physical Prehabilitation in Lung Transplant Candidates: A Proof-of-Concept Study.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Divya MohanMedical Innovation, Value Evidence and Outcomes, GlaxoSmithKline, Collegeville, Pennsylvania.
Victoria S BensonEpidemiology, Value Evidence and Outcomes, GlaxoSmithKline, Middlesex, United Kingdom.
Matthew AllinderQuantitative Sciences and Statistics, GlaxoSmithKline, Collegeville, Pennsylvania.
Nicholas GalweyQuantitative Sciences and Statistics, GlaxoSmithKline, Stevenage, United Kingdom.
Charlotte E BoltonNational Institute for Health Research, Nottingham Biomedical Research Centre, Respiratory Theme and Department of Respiratory Medicine, University of Nottingham, School of Medicine, City Hospital, Nottingham University Hospitals National Health Service Trust Campus, Nottingham, United Kingdom.
John R CockcroftDepartment of Cardiology, Wales Heart Research Institute, Cardiff University, Cardiff, United Kingdom.
William MacNeeMedical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Ian B WilkinsonUniversity of Cambridge, Division of Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, Cambridge, United Kingdom.
Ruth Tal-SingerMedical Innovation, Value Evidence and Outcomes, GlaxoSmithKline, Collegeville, Pennsylvania.
Michael I PolkeyNational Institute for Health Research, Respiratory Biomedical Research Unit, Royal Brompton and Harefield National Health Service Foundation Trust and Imperial College, London, United Kingdom.
ERICA Consortium

Funding

Innovate UKThe United Kingdom Clinical Research Network
6 · The paper itself

Abstract

objectiveTo identify phenotypic factors associated with the Short Physical Performance Battery (SPPB) and its individual sub-tests: standing balance, 4‑meter gait speed (4mGS) and 5-repetition sit-to-stand (5STS).

methodsThe Evaluation of the Role of Inflammation in non-pulmonary disease manifestations in Chronic Airways disease (ERICA) study recruited adult participants with stable chronic obstructive pulmonary disease (COPD). Proportional odds models identified factors associated with the SPPB, and a principal component analysis (PCA) evaluated how much SPPB variance was explainable by each of its 3 sub-tests.

resultsOf 729 enrolled participants, 717 (60% male, mean age 67 years) had full SPPB data. Overall, 76% of patients had some evidence of functional limitations (SPPB total score < 12). Scores < 4 were observed in 71%, 31%, and 22% of participants for the 5STS, 4mGS, and balance sub-tests, respectively. A longer 6-minute walk test and greater quadriceps maximal voluntary contraction decreased the odds of being in a lower score category for SPPB total score and for all 3 sub-tests. Aging, self-reported hypertension and higher dyspnea increased the odds, and being married decreased the odds of being in a lower category for total score. All sub-tests contributed equally to total score.

conclusionEach of the 3 sub-tests contributed independent information to the SPPB, demonstrating their usefulness for assessing COPD when considered together rather than individually. The 5STS sub-test had the greatest variation in scores and may thus have the best discriminatory power for clinical COPD studies of lower limb performance where only one SPPB test is feasible.

Indexed as

4-meter gait speed5-repetition sit-to-standchronic obstructive pulmonary diseasecopdcross-sectional studyShort Physical Performance Battery test

Identifiers

PMID31999899
PMCPMC7182385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.