Evidence map›Paper›PMID 31999864›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Thioguanosine Conversion Enables mRNA-Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC-seq DUAL).

Catherina Gasser, Isabel Delazer, Eva Neuner, Katharina Pascher, Karl Brillet, Sarah Klotz, Lukas Trixl, Maximilian Himmelstoß, Eric Ennifar, Dietmar Rieder and 2 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Metabolic labeling of RNA using ribonucleoside analogs enables the evaluation of RNA synthesis and degradation rates.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  3. Transcriptome and Temporal Transcriptome Analyses in Single Cells.International journal of molecular sciences · 2024
    Review
  4. RSC chemical biology · 2024
    Article
  5. Article
  6. aFundamental research · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Catherina GasserInstitute of Organic Chemistry and Center for Molecular Biosciences, Leopold-Franzens University, Innrain 80, 6020, Innsbruck, Austria.
Isabel DelazerInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innrain 82, 6020, Innsbruck, Austria.
Eva NeunerInstitute of Organic Chemistry and Center for Molecular Biosciences, Leopold-Franzens University, Innrain 80, 6020, Innsbruck, Austria.
Katharina PascherInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innrain 82, 6020, Innsbruck, Austria.
Karl BrilletUniversité de Strasbourg, Architecture et Réactivité de l'ARN-CNRS UPR 9002, Institut de Biologie Moléculaire et Cellulaire, 67000, Strasbourg, France.
Sarah KlotzInstitute of Organic Chemistry and Center for Molecular Biosciences, Leopold-Franzens University, Innrain 80, 6020, Innsbruck, Austria.
Lukas TrixlInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innrain 82, 6020, Innsbruck, Austria.
Maximilian HimmelstoßInstitute of Organic Chemistry and Center for Molecular Biosciences, Leopold-Franzens University, Innrain 80, 6020, Innsbruck, Austria.
Eric EnnifarUniversité de Strasbourg, Architecture et Réactivité de l'ARN-CNRS UPR 9002, Institut de Biologie Moléculaire et Cellulaire, 67000, Strasbourg, France.
Dietmar RiederInstitute of Bioinformatics, Biocenter, Medical University of Innsbruck, Innrain 82, 6020, Innsbruck, Austria.ORCID 0000-0003-1754-690X
Alexandra LusserInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innrain 82, 6020, Innsbruck, Austria.ORCID 0000-0002-2226-9081
Ronald MicuraInstitute of Organic Chemistry and Center for Molecular Biosciences, Leopold-Franzens University, Innrain 80, 6020, Innsbruck, Austria.ORCID 0000-0003-2661-6105

Funding

Austrian Science Fund FWF P 27024
6 · The paper itself

Abstract

Temporal information about cellular RNA populations is essential to understand the functional roles of RNA. We have developed the hydrazine/NH

Indexed as

Base SequenceGuanosineHydrazinesRNA, MessengerRNA StabilitySequence Analysis, RNAStaining and LabelingThionucleosides6-thioguanosineGuanosinehydrazineHydrazinesRNA, MessengerThionucleosidesgene expressionnucleoside modificationsoligonucleotidesRNA sequencingRNA structures

Identifiers

PMID31999864
PMCPMC7186826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.