Evidence map›Paper›PMID 31999732›Full record

ArticlePLoS neglected tropical diseases2020

What constitutes a neglected tropical disease?

Peter J Hotez, Serap Aksoy, Paul J Brindley, Shaden Kamhawi

Abstract readEditorial
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Beyond Borders-Tackling Neglected Tropical Viral Diseases.Tropical medicine and infectious disease · 2026
    Article
  10. Article
  11. Review
  12. Molecular characterization ofFrontiers in veterinary science · 2026
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Bioprospecting for Anti-Kinetoplastid Drug Discovery fromInternational journal of molecular sciences · 2025
    Article
  18. Article
  19. One Health and Neglected Zoonotic Diseases.Pathogens (Basel, Switzerland) · 2025
    Article
  20. Leptospirosis.Nature reviews. Disease primers · 2025
    Review

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peter J HotezDepartments of Pediatrics and Molecular Virology & Microbiology, Texas Children's Hospital Center for Vaccine Development, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States of America.ORCID 0000-0001-8770-1042
Serap AksoyDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, United States of America.ORCID 0000-0001-9941-143X
Paul J BrindleyDepartment of Microbiology, Immunology, and Tropical Medicine, George Washington University School of Medicine, Washington, DC, United States of America.ORCID 0000-0003-1765-0002
Shaden KamhawiVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America.ORCID 0000-0003-4304-636X

Funding

Targeting parasite-host communication to combat liver fluke-induced bile duct cancerR01CA164719 · NCI · GEORGE WASHINGTON UNIVERSITY · PI Paul J Brindley, THEWARACH LAHA · 2012 to 2026
$5.0M
NCI NIH HHS R01 CA164719
6 · The paper itself

Abstract

The World Health Organization (WHO) currently classifies 20 diseases and conditions as neglected tropical diseases (NTDs). However, since its inception in 2007, PLOS Neglected Tropical Diseases has considered an expanded list that includes additional diseases with the chronic and/or debilitating, and poverty-promoting features of NTDs. Described here is an update of our current scope, which attempts to embrace all of the NTDs, and a discussion of the status of some of the more debated medical conditions in terms of whether or not they constitute an NTD.

Indexed as

Tropical ClimateGlobal HealthHumansNeglected DiseasesPovertyWorld Health Organization

Identifiers

PMID31999732
PMCPMC6991948

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.