Evidence map›Paper›PMID 31999567›Full record

ArticleDevelopmental cognitive neuroscience2020

Individualised MRI training for paediatric neuroimaging: A child-focused approach.

Emmanuel Peng Kiat Pua, Sarah Barton, Katrina Williams, Jeffrey M Craig, Marc L Seal

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Article in Developmental cognitive neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  7. Sex-Specific Associations of Irritability With Subcortical Brain Volumes.Biological psychiatry global open science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emmanuel Peng Kiat PuaMelbourne School of Psychological Sciences, University of Melbourne, Australia; Developmental Imaging, Murdoch Children's Research Institute, Australia. Electronic address: emmanuel.pua@mcri.edu.au.
Sarah BartonDevelopmental Imaging, Murdoch Children's Research Institute, Australia; Department of Paediatrics, University of Melbourne, Australia; Department of Neurology, The Royal Children's Hospital, Australia.
Katrina WilliamsDepartment of Paediatrics, University of Melbourne, Australia; Department of Paediatrics, Monash University, Australia; Neurodisability and Rehabilitation, Murdoch Children's Research Institute, Australia.
Jeffrey M CraigDepartment of Paediatrics, University of Melbourne, Australia; Molecular Epidemiology, Murdoch Children's Research Institute, Australia; Centre for Molecular and Medical Research, Deakin University School of Medicine, Geelong, Australia.
Marc L SealDevelopmental Imaging, Murdoch Children's Research Institute, Australia; Department of Paediatrics, University of Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic Resonance Imaging (MRI) in paediatric cohorts is often complicated by reluctance to enter the scanner and head motion-related imaging artefacts. The process is particularly challenging for children with neurodevelopmental disorders where coping with novel task demands in an unfamiliar setting may be more difficult due to symptom-related deficits or distress. These issues often give rise to excessive head motion that can significantly reduce the quality of images acquired, or render data unusable. Here we report an individualised MRI training procedure that enables children with Autism Spectrum Disorders (ASD) to better tolerate the MRI scanner environment based on a child-focused approach and individualised familiarisation strategies, including a pre-visit interview, familiarisation package, and personalised rewards. A medical imaging mobile application was utilised to familiarise participants to multi-sensory aspects of the neuroimaging experience through a variety of themed mini-games and activities. The MRI training procedure was implemented for monozygotic twins (n = 12; 6 twin pairs; age range 7.1-12.9 years) concordant or discordant for ASD. MRI image quality indices were better or comparable to images acquired from a large independent multi-centre ASD cohort. Present findings are promising and suggest that child-focused strategies could improve the quality of paediatric neuroimaging in clinical populations.

Indexed as

Autism Spectrum DisorderBrainChildFemaleHumansMagnetic Resonance ImagingMaleNeurodevelopmental DisordersNeuroimagingAutism spectrum disordersMagnetic resonance imagingNeruodevelopmental disordersNeuroimagingPaediatric

Identifiers

PMID31999567
PMCPMC6994628

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.