Evidence map›Paper›PMID 31999535›Full record

ArticleCirculation research2020

From GWAS Association to Function: Candidate Gene Screening Within Insulin Resistance-Associated Genomic Loci Using a Preadipocyte Differentiation Model.

Feria A Ladha, Michael L Stitzel, J Travis Hinson

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Feria A LadhaFrom the Department of Genetics and Genome Sciences (F.A.L., M.L.S., J.T.H.), UConn Health, Farmington, CT.
Michael L StitzelFrom the Department of Genetics and Genome Sciences (F.A.L., M.L.S., J.T.H.), UConn Health, Farmington, CT.
J Travis HinsonFrom the Department of Genetics and Genome Sciences (F.A.L., M.L.S., J.T.H.), UConn Health, Farmington, CT.

Funding

Comprehensive Analysis of Allelic, Cellular and Molecular Heterogeneity in Human 3-Dimensional Cardiac Microtissues with MYH7 MutationsR01HL142787 · NHLBI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HINSON, JOHN TRAVIS · 2018 to 2021
$2.1M
Regulation and Function of the Type 2 Diabetes-Associated C2CD4A/B LocusR01DK117137 · NIDDK · JACKSON LABORATORY · PI STITZEL, MICHAEL LEE · 2019 to 2023
$2.1M
Metabolic and developmental regulation by AMPK in PRKAG2-associated cardiomyopathyK08HL125807 · NHLBI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HINSON, JOHN TRAVIS · 2015 to 2019
$803k
Human cardiac microtissues with innate immune sensing to study adverse consequences of genome editingU01EB028898 · NIBIB · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HINSON, JOHN TRAVIS · 2019 to 2019
$752k
NHLBI NIH HHS K08 HL125807NHLBI NIH HHS R01 HL142787NIBIB NIH HHS U01 EB028898NIDDK NIH HHS R01 DK117137
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Insulin ResistanceAdipocytesCell DifferentiationGenome-Wide Association StudyGenomicsHumansadipocytesdiabetes type 2Editorialsglucoseinsulin resistance

Identifiers

PMID31999535
PMCPMC7000166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.