ArticleJournal of the American Chemical Society2020
δ-C-H Mono- and Dihalogenation of Alcohols.
Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 94 citations in OpenAlex.
- Cobalt-Catalyzed γ‑C-H Functionalization of Alcohols via Olefin-Tethered Radical Relay.JACS Au · 2026Article
- Thermally activated delayed fluorescence materials: innovative design and advanced application in biomedicine, catalysis and electronics.RSC advances · 2025Review
- Switchable Site-Selective Benzanilide C(spMolecules (Basel, Switzerland) · 2024Article
- Metal-free photoinduced C(spNature communications · 2023Article
- Electrochemical Deconstructive Functionalization of Cycloalkanols via Alkoxy Radicals Enabled by Proton-Coupled Electron Transfer.Organic letters · 2022Article
- δ-C-H Halogenation Reactions Enabled by a Nitrogen-Centered Radical Precursor.Organic letters · 2022Article
- Site-selective coupling of remote C(spChemical science · 2022Article
- Catalytic remote hydrohalogenation of internal alkenes.Nature chemistry · 2022Article
- Site Selective Chlorination of C(spAngewandte Chemie (International ed. in English) · 2021Article
- Energy Read-out as a Probe of Kinetically Hidden Transition States.Organic letters · 2021Article
- Photo-induced copper-catalyzed alkynylation and amination of remote unactivated C(spChemical science · 2021Article
- Catalytic generation of alkoxy radicals from unfunctionalized alcohols.Chemical science · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Alkoxy radicals have long been known to enable remote C-H functionalization via 1,5-hydrogen atom abstraction. However, methods for their generation traditionally have relied upon highly oxidizing metals, ultraviolet radiation, or preformed peroxide intermediates, which has prevented the development of many desirable transformations. Herein we report a new bench-stable precursor that decomposes to free alkoxy radicals via a previously unreported single-electron oxidation pathway. This new precursor enables the fluorination and chlorination of remote C-H bonds under exceptionally mild conditions with exceedingly high monoselectivity. Iterative use of this precursor enables the introduction of a second halogen atom, granting access to remote dihalide motifs, including CF
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.