Evidence map›Paper›PMID 31999397›Full record

ArticleNMR in biomedicine2021

On the acquisition of the water signal during water suppression: High-speed MR spectroscopic imaging with water referencing and concurrent functional MRI.

Stefan Posse, Bruno Sa De La Rocque Guimaraes, Troy Hutchins-Delgado, Kishore Vakamudi, Kevin Fotso Tagne, Steen Moeller, Stephen R Dager

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Parallel detection of MRI andMagnetic resonance in medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Stefan PosseDepartment of Neurology, University of New Mexico, Albuquerque, New, Mexico, USA.ORCID 0000-0002-4816-080X
Bruno Sa De La Rocque GuimaraesDepartment of Neurology, University of New Mexico, Albuquerque, New, Mexico, USA.
Troy Hutchins-DelgadoDepartment of Neurology, University of New Mexico, Albuquerque, New, Mexico, USA.
Kishore VakamudiDepartment of Neurology, University of New Mexico, Albuquerque, New, Mexico, USA.
Kevin Fotso TagneDepartment of Neurology, University of New Mexico, Albuquerque, New, Mexico, USA.
Steen MoellerCenter for Magnetic Resonance Research, Radiology, University of Minnesota, Minneapolis, Minnesota, USA.
Stephen R DagerDepartments of Radiology and Bioengineering, University of Washington, Seattle, Washington, USA.
University of New Mexico · USUniversity of Minnesota · USUniversity of Washington · US

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
HIGH FIELD MR RESEARCH IN DRUG ABUSER01DA014178 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI RENSHAW, PERRY FRANKLIN · 2001 to 2005
$3.5M
A Longitudinal 3-D MRSI Study of Infants at High Risk for AutismR01HD065283 · NICHD · UNIVERSITY OF WASHINGTON · PI DAGER, STEPHEN R · 2009 to 2010
$445k
Diffusion tensor MR spectroscopic imaging in human brainR21EB011606 · NIBIB · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI POSSE, STEFAN · 2011 to 2012
$389k
Concurrent High-Speed fMRI and Diffusion Tensor MRSIR21CA241714 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI POSSE, STEFAN · 2019 to 2021
$374k
NCI NIH HHS R21 CA241714NIBIB NIH HHS P41 EB015894NIBIB NIH HHS P41 EB027061NIBIB NIH HHS R21 EB011606NICHD NIH HHS R01 HD065283NIDA NIH HHS R01 DA014178
6 · The paper itself

Abstract

This study evaluated the utility of concurrent water signal acquisition as part of the water suppression in MR spectroscopic imaging (MRSI), to allow simultaneous water referencing for metabolite quantification, and to concurrently acquire functional MRI (fMRI) data. We integrated a spatial-spectral binomial water excitation RF pulse and a short spatial-spectral echo-planar readout into the water suppression module of 2D and 3D proton-echo-planar-spectroscopic-imaging (PEPSI) with a voxel size as small as 4 x 4 x 6 mm

Indexed as

Magnetic Resonance ImagingSignal Processing, Computer-AssistedAdolescentAdultBrainFemaleHumansInfantMaleMetabolomeMiddle AgedRadio WavesWaterYoung AdultWaterfunctional MRI acquisition techniques (BOLD and non-BOLD)multimodality imagingquantitative MRSresting-state functional MRIsampling strategiesspectroscopic imagingwater referencing

Identifiers

PMID31999397
PMCPMC7390701
OpenAlexW3003204572

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.