Evidence map›Paper›PMID 31998842›Full record

ArticleScience advances2020

Antibiotic production in

Zheren Zhang, Chao Du, Frédérique de Barsy, Michael Liem, Apostolos Liakopoulos, Gilles P van Wezel, Young H Choi, Dennis Claessen, Daniel E Rozen

Abstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Review
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  14. Generalizing the central dogma as a cross-hierarchical principle of biology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  15. Factors that influence the caste ratio in a bacterial division of labour.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  16. The evolution of division of labour: preconditions and evolutionary feedback.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zheren ZhangInstitute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.ORCID 0000-0001-6384-3054
Chao DuInstitute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.ORCID 0000-0003-3447-5293
Frédérique de BarsyInstitute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.ORCID 0000-0002-9571-7316
Michael LiemInstitute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.
Apostolos LiakopoulosInstitute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.
Gilles P van WezelInstitute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.ORCID 0000-0003-0341-1561
Young H ChoiNatural Products Laboratory, Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.ORCID 0000-0003-1484-1700
Dennis ClaessenInstitute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.ORCID 0000-0002-0789-2633
Daniel E RozenInstitute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, Netherlands.ORCID 0000-0002-7772-0239

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the hallmark behaviors of social groups is division of labor, where different group members become specialized to carry out complementary tasks. By dividing labor, cooperative groups increase efficiency, thereby raising group fitness even if these behaviors reduce individual fitness. We find that antibiotic production in colonies of

Indexed as

Gene Expression Regulation, BacterialGenes, BacterialAnti-Bacterial AgentsGenetic HeterogeneityGenome, BacterialGenomicsMutationPhenotypeProteomeSecondary MetabolismStreptomycesAnti-Bacterial AgentsProteome

Identifiers

PMID31998842
PMCPMC6962034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.