Evidence map›Paper›PMID 31998560›Full record

ArticlePeerJ2020

Differentially expressed genes and key molecules of

Yue Li, Xiaoyan Zhou, Jiali Liu, Yang Yin, Xiaohong Yuan, Ruihua Yang, Qi Wang, Jing Ji, Qian He

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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  13. Transcriptome Patterns ofInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yue LiDepartment of Clinical Laboratories, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xiaoyan ZhouDepartment of Clinical Laboratories, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jiali LiuDepartment of Clinical Laboratories, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yang YinDepartment of Clinical Laboratories, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xiaohong YuanDepartment of Clinical Laboratories, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Ruihua YangDepartment of Clinical Laboratories, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Qi WangDepartment of Clinical Laboratories, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jing JiDepartment of Clinical Laboratories, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Qian HeDepartment of Clinical Laboratories, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Second Affiliated Hospital of Xi'an Jiaotong University · CNChina XD Group (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsGene expression profiles from The Cancer Genome Atlas (TCGA) database were downloaded and combined with cBioPortal website to identify exact breast cancer patients with

resultsThe regulation process of cell cycle was significantly enriched in mutant group compared with wild-type group. A total of 294 genes were identified after analysis of DEGs between mutant patients and wild-type patients. Interestingly, by the other two comparisons, we identified 43 overlapping genes that not only significantly expressed in wild-type breast cancer patients relative to normal tissues, but more significantly expressed in

conclusionOur research provides comprehensive and new insights for the identification of biomarkers connected with

Indexed as

BRCA1/2 mutationsBreast cancerdiagnostic valueDifferentially expressed genesSurvival analysis

Identifiers

PMID31998560
PMCPMC6979404
OpenAlexW3002801767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.