Evidence map›Paper›PMID 31998557›Full record

ArticlePeerJ2020

Appetite regulating genes may contribute to herbivory versus carnivory trophic divergence in haplochromine cichlids.

Ehsan P Ahi, Anna Duenser, Pooja Singh, Wolfgang Gessl, Christian Sturmbauer

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Ehsan P AhiEvolutionary Biology Centre, Uppsala University, Uppsala, Sweden.
Anna DuenserInstitute of Biology, University of Graz, Graz, Austria.
Pooja SinghInstitute of Biology, University of Graz, Graz, Austria.
Wolfgang GesslInstitute of Biology, University of Graz, Graz, Austria.
Christian SturmbauerInstitute of Biology, University of Graz, Graz, Austria.
University of Graz · ATUniversity of Calgary · CA

Funding

Austrian Science Fund FWF P 29838
6 · The paper itself

Abstract

Feeding is a complex behaviour comprised of satiety control, foraging, ingestion and subsequent digestion. Cichlids from the East African Great Lakes are renowned for their diverse trophic specializations, largely predicated on highly variable jaw morphologies. Thus, most research has focused on dissecting the genetic, morphological and regulatory basis of jaw and teeth development in these species. Here for the first time we explore another aspect of feeding, the regulation of appetite related genes that are expressed in the brain and control satiety in cichlid fishes. Using qPCR analysis, we first validate stably expressed reference genes in the brain of six haplochromine cichlid species at the end of larval development prior to foraging. We next evaluate the expression of 16 appetite related genes in herbivorous and carnivorous species from the parallel radiations of Lake Tanganyika, Malawi and Victoria. Interestingly, we find increased expression of two appetite-regulating genes (anorexigenic genes),

Indexed as

Adaptive radiationAnorexigenicAppetite regulationBrainCichlidsEast African LakesGene expressionLarval developmentOrexigenicTrophic specialization

Identifiers

PMID31998557
PMCPMC6977467
OpenAlexW2956191343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.