Evidence map›Paper›PMID 31998434›Full record

ReviewOxidative medicine and cellular longevity2020

Cardioprotective Effects of Dietary Phytochemicals on Oxidative Stress in Heart Failure by a Sex-Gender-Oriented Point of View.

Klara Komici, Valeria Conti, Sergio Davinelli, Leonardo Bencivenga, Giuseppe Rengo, Amelia Filippelli, Nicola Ferrara, Graziamaria Corbi

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Food science & nutrition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Klara KomiciDepartment of Medicine and Health Sciences, University of Molise, Via Francesco De Sanctis, 1, 86100 Campobasso, Italy.ORCID https://orcid.org/0000-0001-9419-2426
Valeria ContiDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via S. Allende, Baronissi, 84081 Salerno, Italy.ORCID https://orcid.org/0000-0001-6964-2739
Sergio DavinelliDepartment of Medicine and Health Sciences, University of Molise, Via Francesco De Sanctis, 1, 86100 Campobasso, Italy.ORCID https://orcid.org/0000-0003-2578-7199
Leonardo BencivengaDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini, 5 -, 80138 Naples, Italy.ORCID https://orcid.org/0000-0002-9575-8337
Giuseppe RengoDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini, 5 -, 80138 Naples, Italy.ORCID https://orcid.org/0000-0002-9701-0437
Amelia FilippelliDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via S. Allende, Baronissi, 84081 Salerno, Italy.ORCID https://orcid.org/0000-0002-8235-9118
Nicola FerraraDepartment of Translational Medical Sciences, University of Naples Federico II, Via Pansini, 5 -, 80138 Naples, Italy.ORCID https://orcid.org/0000-0001-8200-4942
Graziamaria CorbiDepartment of Medicine and Health Sciences, University of Molise, Via Francesco De Sanctis, 1, 86100 Campobasso, Italy.ORCID https://orcid.org/0000-0002-3441-889X
University of Molise · ITIstituti Clinici Scientifici Maugeri · ITUniversity of Salerno · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary phytochemicals are considered an innovative strategy that helps to reduce cardiovascular risk factors. Some phytochemicals have been shown to play a beneficial role in lipid metabolism, to improve endothelial function and to modify oxidative stress pathways in experimental and clinical models of cardiovascular impairment. Importantly, investigation on phytochemical effect on cardiac remodeling appears to be promising. Nowadays, drug therapy and implantation of devices have demonstrated to ameliorate survival. Of interest, sex-gender seems to influence the response to HF canonical therapies. In fact, starting by the evidence of the feminization of world population and the scarce efficacy and safety of the traditional drugs in women, the search of alternative therapeutic tools has become mandatory. The aim of this review is to summarize the possible role of dietary phytochemicals in HF therapy and the evidence of a different sex-gender-oriented response.

Indexed as

AntioxidantsFemaleHeart FailureHumansMaleOxidative StressPhytochemicalsAntioxidantsPhytochemicals

Identifiers

PMID31998434
PMCPMC6975222
OpenAlexW3000145678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.