Evidence map›Paper›PMID 31998326›Full record

ArticleFrontiers in immunology2019

Microenvironment-Dependent Gradient of CTL Exhaustion in the AE17sOVA Murine Mesothelioma Tumor Model.

Jennifer L Hope, Panagiota I Spantidea, Caoimhe H Kiernan, Christopher J Stairiker, Laurine C Rijsbergen, Marjan van Meurs, Inge Brouwers-Haspels, Yvonne M Mueller, Delia J Nelson, Linda M Bradley and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Jennifer L HopeDepartment of Immunology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Panagiota I SpantideaDepartment of Immunology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Caoimhe H KiernanDepartment of Immunology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Christopher J StairikerDepartment of Immunology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Laurine C RijsbergenDepartment of Immunology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Marjan van MeursDepartment of Immunology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Inge Brouwers-HaspelsDepartment of Immunology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Yvonne M MuellerDepartment of Immunology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Delia J NelsonImmunology and Cancer Group, School of Biomedical Sciences, Curtin University, Perth, WA, Australia.
Linda M BradleyCancer Immunology and Tumor Microenvironment Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Joachim G J V AertsDepartment of Pulmonary Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Peter D KatsikisDepartment of Immunology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Erasmus MC · NLCurtin University · AUDiscovery Institute · USSanford Burnham Prebys Medical Discovery Institute · US

Funding

Worldwide Cancer Research 16-1153
6 · The paper itself

Abstract

The immune system, and in particular, cytotoxic CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesCells, CulturedDisease Models, AnimalFemaleImmunotherapyLymphocyte ActivationMesotheliomaMiceMice, Inbred C57BLT-Lymphocytes, CytotoxicTumor MicroenvironmentcancerCD8+ T cellsperipheral lymphoid organsT cell exhaustiontumors

Identifiers

PMID31998326
PMCPMC6968785
OpenAlexW3000271305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.