ReviewFrontiers in immunology2019
Neutrophil Subsets in Periodontal Health and Disease: A Mini Review.
Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07508839 (Evaluation of the Safety and Efficacy of SALI-10 Probiotic Lozenges), which is not on this map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Safety and Efficacy of SALI-10 Probiotic Lozenges: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial
Who cites it
31 citing papers in PubMed.
- CHAC2-mediated glutathione metabolic reprogramming drives N1 polarization of bone marrow neutrophils and exacerbates inflammatory comorbidities.International journal of oral science · 2026Article
- Obesity and periodontal diseases: A review.Bioinformation · 2026Article
- Prognostic utility of oral neutrophil counts in high-risk periodontitis: A retrospective study.Journal of periodontology · 2025Article
- Neutrophil activity compromises root caries remineralization and alters caries-affected-like dentin.Clinical oral investigations · 2025Article
- Engineered Tissue Models to Decode Host-Microbiota Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Infectious and Immunological Links Between Periodontitis and COVID-19: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Secretory leucocyte protease inhibitor regulates bone metabolism and inflammation in experimental mouse periodontitis.Communications biology · 2025Article
- Limited proteolysis of neutrophil granule proteins by the bacterial protease RgpB depletes neutrophil antimicrobial capacity.Journal of leukocyte biology · 2025Article
- Periodontal diseases in Down syndrome during childhood: a scoping review.BMC oral health · 2025Article
- Association between neutrophil-percentage-to-albumin ratio and periodontitis: insights from a population-based study.Frontiers in nutrition · 2025Article
- Article
- Toward Digital Periodontal Health: Recent Advances and Future Perspectives.Bioengineering (Basel, Switzerland) · 2024Review
- Local Drug Delivery Systems as Novel Approach for Controlling NETosis in Periodontitis.Pharmaceutics · 2024Review
- Evaluation of NETosis (Neutrophil Extracellular Traps) biomarkers in smokers and nonsmokers periodontitis patients.F1000Research · 2024Article
- The double-edged role of neutrophil heterogeneity in inflammatory diseases and cancers.MedComm · 2023Review
- Identification of Immune Infiltration in Odontogenic Keratocyst by Integrated Bioinformatics Analysis.BMC oral health · 2023Article
- Understanding the functional relevance of oral neutrophils, phenotype and properties in OSCC.Medical oncology (Northwood, London, England) · 2023Review
- Neutrophils are gatekeepers of mucosal immunity.Immunological reviews · 2023Review
- Ropinirole inhibits inflammatory cytokine production in gingival epithelial cells and suppresses alveolar bone loss in an experimental rat model of periodontitis.Experimental and therapeutic medicine · 2023Article
- Innovative biomaterials for the treatment of periodontal disease.Frontiers in dental medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neutrophils are amongst the most abundant immune cells within the periodontal tissues and oral cavity. As innate immune cells, they are first line defenders at the tooth-mucosa interface, and can perform an array of different functions. With regard to these, it has been observed over many years that neutrophils are highly heterogeneous in their behavior. Therefore, it has been speculated that neutrophils, similarly to other leukocytes, exist in distinct subsets. Several studies have investigated different markers of neutrophils in oral health and disease in recent years in order to define potential cell subsets and their specific tasks. This research was inspired by recent advancements in other fields of medicine in this field. The aim of this review is to give an overview of the current evidence regarding the existence and presence of neutrophil subsets and their possible functions, specifically in the context of periodontitis, gingivitis, and periodontal health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.