Evidence map›Paper›PMID 31998255›Full record

ArticleFrontiers in microbiology2019

Mygalin: An Acylpolyamine With Bactericidal Activity.

Abraham Espinoza-Culupú, Elizabeth Mendes, Hector Aguilar Vitorino, Pedro Ismael da Silva, Monamaris Marques Borges

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Antimicrobial activity and partial chemical structure of acylpolyamines isolated from the venom of the spiderThe journal of venomous animals and toxins including tropical diseases · 2022
    Article
  6. Brazilian Theraphosidae: a toxicological point of view.The journal of venomous animals and toxins including tropical diseases · 2021
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Abraham Espinoza-CulupúPh.D. Program in Biotechnology, University of São Paulo, São Paulo, Brazil.
Elizabeth MendesBacteriology Laboratory, Butantan Institute, São Paulo, Brazil.
Hector Aguilar VitorinoInstitute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Columbus Center, Baltimore, MD, United States.
Pedro Ismael da SilvaLaboratory for Applied Toxinology (LETA), Butantan Institute, São Paulo, Brazil.
Monamaris Marques BorgesBacteriology Laboratory, Butantan Institute, São Paulo, Brazil.
Instituto Butantan · BRColumbus Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inappropriate use of antibiotics favors the selection and spread of resistant bacteria. To reduce the spread of these bacteria, finding new molecules with activity is urgent and necessary. Several polyamine analogs have been constructed and used to control microorganisms and tumor cells. Mygalin is a synthetic acylpolyamine, which are analogs of spermidine, derived from the hemolymph of the spider

Indexed as

acylpolyamineantimicrobialbiomoleculeE. coliMygalinoxidative stress

Identifiers

PMID31998255
PMCPMC6965172
OpenAlexW2999261285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.