Evidence map›Paper›PMID 31998139›Full record

ArticleFrontiers in physiology2019

Mast Cells in Peritoneal Fluid From Women With Endometriosis and Their Possible Role in Modulating Sperm Function.

Violetta Borelli, Monica Martinelli, Stefania Luppi, Francesca Vita, Federico Romano, Francesco Fanfani, Elisa Trevisan, Fulvio Celsi, Giuliano Zabucchi, Fabrizio Zanconati and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Violetta BorelliDepartment of Life Sciences, University of Trieste, Trieste, Italy.
Monica MartinelliInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
Stefania LuppiInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
Francesca VitaDepartment of Life Sciences, University of Trieste, Trieste, Italy.
Federico RomanoInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
Francesco FanfaniUOC di Ginecologia Oncologica, Dipartimento Scienze della Salute della Donna e del Bambino, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Elisa TrevisanDepartment of Life Sciences, University of Trieste, Trieste, Italy.
Fulvio CelsiDepartment of Life Sciences, University of Trieste, Trieste, Italy.
Giuliano ZabucchiDepartment of Life Sciences, University of Trieste, Trieste, Italy.
Fabrizio ZanconatiDepartment of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
Cristina BottinDepartment of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
Giuseppe RicciInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
University of Trieste · ITIRCCS Materno Infantile Burlo Garofolo · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a local pelvic inflammatory process, frequently associated with infertility, with altered function of immune-related cells in the peritoneal environment. Mast cells are known to be key players of the immune system and have been recently involved in endometriosis and in infertility, with their mediators directly suppressing sperm motility. In this study, we evaluated the mast cell population and their mediators in the peritoneal fluid of infertile patients with endometriosis and their impact on human sperm motility. Peritoneal fluids, collected by laparoscopy from 11 infertile patients with endometriosis and 9 fertile controls were evaluated for the presence of mast cells, tryptase levels and their effect on sperm motility. Furthermore, an

Indexed as

endometriosisinfertilitymast cellsspermtryptase

Identifiers

PMID31998139
PMCPMC6964357
OpenAlexW2999633128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.