ArticleFrontiers in systems neuroscience2019
Neural Correlates of Vestibular Processing During a Spaceflight Analog With Elevated Carbon Dioxide (CO
Article in Frontiers in systems neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- The human brain in space: a meta-analysis of neuroimaging evidence.Frontiers in psychology · 2026Pooled it
- Spaceflight-associated neuro-ocular syndrome (SANS): expert consensus on diagnosis and management.Eye (London, England) · 2026Review
- The microgravity environment affects sensorimotor adaptation and its neural correlates.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Thirty minutes of daily artificial gravity does not mitigate head down tilt induced brain activity changes during cognitive task performance.Frontiers in neurology · 2025Article
- Daily artificial gravity partially mitigates vestibular processing changes associated with head-down tilt bedrest.NPJ microgravity · 2024Article
- Dynamic changes in perivascular space morphology predict signs of spaceflight-associated neuro-ocular syndrome in bed rest.NPJ microgravity · 2024Article
- Longitudinal Changes in Cerebral Perfusion, Perivascular Space Volume, and Ventricular Volume in a Healthy Cohort Undergoing a Spaceflight Analog.AJNR. American journal of neuroradiology · 2023Article
- Daily artificial gravity is associated with greater neural efficiency during sensorimotor adaptation.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The effect of long-term spaceflight on drug potency and the risk of medication failure.NPJ microgravity · 2023Article
- Cognition in zero gravity: Effects of non-terrestrial gravity on human behaviour.Quarterly journal of experimental psychology (2006) · 2023Article
- Changes in working memory brain activity and task-based connectivity after long-duration spaceflight.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Prolonged microgravity induces reversible and persistent changes on human cerebral connectivity.Communications biology · 2023Article
- Impact of different ground-based microgravity models on human sensorimotor system.Frontiers in physiology · 2023Review
- Sensory system-specific associations between brain structure and balance.Neurobiology of aging · 2022Article
- Brain and Behavioral Evidence for Reweighting of Vestibular Inputs with Long-Duration Spaceflight.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- The Effects of 30 Minutes of Artificial Gravity on Cognitive and Sensorimotor Performance in a Spaceflight Analog Environment.Frontiers in neural circuits · 2022Article
- Effects of 15-Days -6° Head-Down Bed Rest on the Attention Bias of Threatening Stimulus.Frontiers in psychology · 2022Article
- Ophthalmic changes in a spaceflight analog are associated with brain functional reorganization.Human brain mapping · 2021Article
- Microgravity effects on the human brain and behavior: Dysfunction and adaptive plasticity.Neuroscience and biobehavioral reviews · 2021Review
- A review of alterations to the brain during spaceflight and the potential relevance to crew in long-duration space exploration.NPJ microgravity · 2021Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Astronauts return to Earth from spaceflight missions with impaired mobility and balance; recovery can last weeks postflight. This is due in large part to the altered vestibular signaling and sensory reweighting that occurs in microgravity. The neural mechanisms of spaceflight-induced vestibular changes are not well understood. Head-down-tilt bed rest (HDBR) is a common spaceflight analog environment that allows for study of body unloading, fluid shifts, and other consequences of spaceflight. Subjects in this context still show vestibular changes despite being in Earth's gravitational environment, potentially due to sensory reweighting. Previously, we found evidence of sensory reweighting and reduced neural efficiency for vestibular processing in subjects who underwent a 70-day HDBR intervention. Here we extend this work by evaluating the impact of HDBR paired with elevated carbon dioxide (CO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.