ArticleFrontiers in neuroscience2019
Disruption of Early or Late Epochs of Auditory Cortical Activity Impairs Speech Discrimination in Mice.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Decoding auditory cognition: Unraveling the corticostriatal-SNr circuit's role in frequency discrimination accuracy.iScience · 2025Article
- Selectivity to acoustic features of human speech in the auditory cortex of the mouse.Hearing research · 2024Article
- Corticostriatal Neurons in the Anterior Auditory Field Regulate Frequency Discrimination Behavior.Neuroscience bulletin · 2023Article
- What can we learn from inactivation studies? Lessons from auditory cortex.Trends in neurosciences · 2022Review
- More than the end: OFF response plasticity as a mnemonic signature of a sound's behavioral salience.Frontiers in computational neuroscience · 2022Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Speech evokes robust activity in auditory cortex, which contains information over a wide range of spatial and temporal scales. It remains unclear which components of these neural representations are causally involved in the perception and processing of speech sounds. Here we compared the relative importance of early and late speech-evoked activity for consonant discrimination. We trained mice to discriminate the initial consonants in spoken words, and then tested the effect of optogenetically suppressing different temporal windows of speech-evoked activity in auditory cortex. We found that both early and late suppression disrupted performance equivalently. These results suggest that mice are impaired at recognizing either type of disrupted representation because it differs from those learned in training.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.