Evidence map›Paper›PMID 31998003›Full record

ArticlePostepy dermatologii i alergologii2019

Omalizumab usage in chronic urticaria and atopic dermatitis: data from South-East province of Turkey.

Hülya Nazik, Mehmet Kamil Mülayim, Perihan Öztürk

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Presence of positive skin prick tests to inhalant allergens and markers of T2 inflammation in subjects with chronic spontaneous urticaria (CSU): a systematic literature review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hülya NazikDepartment of Dermatology, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey.
Mehmet Kamil MülayimDepartment of Dermatology, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey.
Perihan ÖztürkDepartment of Dermatology, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey.
Kahramanmaraş Sütçü İmam University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOmalizumab is a current treatment option for IgE-associated dermatoses, such as urticaria and atopic dermatitis.

aimTo evaluate the clinical and laboratory findings of patients with chronic urticaria and atopic dermatitis who received omalizumab. MATERIAL AND

methodsThis study was planned as a cross-sectional and retrospective one. One hundred forty-six cases were included in the study. Omalizumab at a dose of 300 mg for patients with chronic urticaria and 600 mg for patients with atopic dermatitis, was given every 4 weeks. The response to the given treatment and remission status of patients were investigated.

resultsOf 146 patients included in the study, 70.5% (

conclusionsThe decline of complaints with different treatment schemes in different patients suggests that treatment should be designed individually and that personal biomarkers playing a role in the effectiveness of the drug are important. Patients with the high IgE and eosinophil percentages and positive autologous serum test had a better treatment response to omalizumab treatment. Meanwhile, remission was found to be more frequent in atopic dermatitis patients with omalizumab treatment compared to the patients with urticaria. It may be more appropriate to choose patients based on certain criteria to ensure cost-effectiveness in omalizumab treatment.

Indexed as

atopic dermatitischronic urticariaimmunoglobulin Eomalizumab

Identifiers

PMID31998003
PMCPMC6986296
OpenAlexW3005033658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.